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- W4249069803 abstract "B lymphocytes activated by antigen and T lymphocytes initiate germinal centres in lymphoid tissues and hypermutate the variable region of their expressed immunoglobulin genes. The mechanism of this somatic hypermutation process depends on transcription. In chicken and rabbits, immunoglobulin gene mutations are created by gene conversion in a process that may have some relationship to cassette switching hypervariation in trypanosomes." @default.
- W4249069803 created "2022-05-12" @default.
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- W4249069803 date "2003-07-22" @default.
- W4249069803 modified "2023-09-23" @default.
- W4249069803 title "Somatic Hypermutation in Antibody Evolution" @default.
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- W4249069803 doi "https://doi.org/10.1038/npg.els.0000842" @default.
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