Matches in SemOpenAlex for { <https://semopenalex.org/work/W4249090882> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4249090882 endingPage "177" @default.
- W4249090882 startingPage "174" @default.
- W4249090882 abstract "A simple undergraduate laboratory experiment that can be used in Biochemistry and Toxicology courses to illustrate the importance of metabolic reactions in the toxicity of chemical substances is reported. It involves the experimental confirmation that oxidized phosphorothionate esters, commonly used as insecticides, are stronger cholinesterase inhibitors and therefore exhibit higher toxicity than do their sulphur analogs starting from which the first are formed by in vivo oxidative desulphuration. Two separated aliquots of a bovine blood sample are incubated with parathion and paraoxon, its oxygen analog, and compared for cholinesterase activity with “normal” blood. Previously, a standard sample of paraoxon was obtained by oxidation of the thiono group of parathion with bromine vapour by reaction TLC. The comparison of the inhibitory capacity of both compounds is made by a colorimetric procedure using acetylthiocholine as substrate of the enzyme and 5,5′-dithiobis-(2-nitrobenzoic acid) as chromogen." @default.
- W4249090882 created "2022-05-12" @default.
- W4249090882 creator A5031036707 @default.
- W4249090882 creator A5058606374 @default.
- W4249090882 creator A5060976408 @default.
- W4249090882 creator A5083734088 @default.
- W4249090882 date "2000-05-01" @default.
- W4249090882 modified "2023-09-26" @default.
- W4249090882 title "Oxidation of cholinesterase-inhibiting pesticides: A simple experiment to illustrate the role of bioactivation in the toxicity of chemicals" @default.
- W4249090882 cites W1604221213 @default.
- W4249090882 cites W1971048984 @default.
- W4249090882 cites W2077950592 @default.
- W4249090882 doi "https://doi.org/10.1111/j.1539-3429.2000.tb00060.x" @default.
- W4249090882 hasPublicationYear "2000" @default.
- W4249090882 type Work @default.
- W4249090882 citedByCount "0" @default.
- W4249090882 crossrefType "journal-article" @default.
- W4249090882 hasAuthorship W4249090882A5031036707 @default.
- W4249090882 hasAuthorship W4249090882A5058606374 @default.
- W4249090882 hasAuthorship W4249090882A5060976408 @default.
- W4249090882 hasAuthorship W4249090882A5083734088 @default.
- W4249090882 hasConcept C111368507 @default.
- W4249090882 hasConcept C127313418 @default.
- W4249090882 hasConcept C161176658 @default.
- W4249090882 hasConcept C178790620 @default.
- W4249090882 hasConcept C181199279 @default.
- W4249090882 hasConcept C185592680 @default.
- W4249090882 hasConcept C2777207434 @default.
- W4249090882 hasConcept C2777289219 @default.
- W4249090882 hasConcept C2777565064 @default.
- W4249090882 hasConcept C2778816929 @default.
- W4249090882 hasConcept C2779059548 @default.
- W4249090882 hasConcept C2909509320 @default.
- W4249090882 hasConcept C29730261 @default.
- W4249090882 hasConcept C31896038 @default.
- W4249090882 hasConcept C43617362 @default.
- W4249090882 hasConcept C55493867 @default.
- W4249090882 hasConcept C6557445 @default.
- W4249090882 hasConcept C71924100 @default.
- W4249090882 hasConcept C86803240 @default.
- W4249090882 hasConcept C98274493 @default.
- W4249090882 hasConceptScore W4249090882C111368507 @default.
- W4249090882 hasConceptScore W4249090882C127313418 @default.
- W4249090882 hasConceptScore W4249090882C161176658 @default.
- W4249090882 hasConceptScore W4249090882C178790620 @default.
- W4249090882 hasConceptScore W4249090882C181199279 @default.
- W4249090882 hasConceptScore W4249090882C185592680 @default.
- W4249090882 hasConceptScore W4249090882C2777207434 @default.
- W4249090882 hasConceptScore W4249090882C2777289219 @default.
- W4249090882 hasConceptScore W4249090882C2777565064 @default.
- W4249090882 hasConceptScore W4249090882C2778816929 @default.
- W4249090882 hasConceptScore W4249090882C2779059548 @default.
- W4249090882 hasConceptScore W4249090882C2909509320 @default.
- W4249090882 hasConceptScore W4249090882C29730261 @default.
- W4249090882 hasConceptScore W4249090882C31896038 @default.
- W4249090882 hasConceptScore W4249090882C43617362 @default.
- W4249090882 hasConceptScore W4249090882C55493867 @default.
- W4249090882 hasConceptScore W4249090882C6557445 @default.
- W4249090882 hasConceptScore W4249090882C71924100 @default.
- W4249090882 hasConceptScore W4249090882C86803240 @default.
- W4249090882 hasConceptScore W4249090882C98274493 @default.
- W4249090882 hasIssue "3" @default.
- W4249090882 hasLocation W42490908821 @default.
- W4249090882 hasOpenAccess W4249090882 @default.
- W4249090882 hasPrimaryLocation W42490908821 @default.
- W4249090882 hasRelatedWork W10347169 @default.
- W4249090882 hasRelatedWork W21376089 @default.
- W4249090882 hasRelatedWork W27589530 @default.
- W4249090882 hasRelatedWork W32817329 @default.
- W4249090882 hasRelatedWork W34672625 @default.
- W4249090882 hasRelatedWork W37490428 @default.
- W4249090882 hasRelatedWork W4014828 @default.
- W4249090882 hasRelatedWork W608547 @default.
- W4249090882 hasRelatedWork W8892984 @default.
- W4249090882 hasRelatedWork W9305923 @default.
- W4249090882 hasVolume "28" @default.
- W4249090882 isParatext "false" @default.
- W4249090882 isRetracted "false" @default.
- W4249090882 workType "article" @default.