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- W4249224981 abstract "Spermatocytic seminoma is a rare testicular neoplasm which occurs only in adults (range 25–87 years, mean 54). It has no ovarian homologue. It is not associated with other types of germ cell neoplasia or with cryptorchidism. Orchiectomy is curative in virtually all cases; of more than 200 known cases, only 1 or 2 have metastasized. In approximately a dozen cases, sarcomas have arisen in the testes in association with spermatocytic seminoma; most of these patients have died of metastatic sarcoma after short intervals. The gross appearance of spermatocytic seminoma is characteristically edematous or gelatinous, and often the tumor is more than 5 cm in diameter. Microscopically, spermatocytic seminoma is seen to be composed of sheets of small, medium, and large cells with spherical nuclei. The chromatin is dense in the small cells and filamentous in the medium and large ones. The cytoplasm is eosinophilic to amphophilic and lacks glycogen. Spermatocytic seminoma is not associated with intratubular germ cell neoplasia of the unclassified type. Analyses of DNA content have failed to show haploid populations, and the lectin binding does not show maturation toward spermatocytes." @default.
- W4249224981 created "2022-05-12" @default.
- W4249224981 creator A5067336495 @default.
- W4249224981 date "2005-07-01" @default.
- W4249224981 modified "2023-09-26" @default.
- W4249224981 title "Spermatocytic Seminoma" @default.
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- W4249224981 doi "https://doi.org/10.1097/01.pcr.0000168823.72440.5a" @default.
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