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• W4249262905 abstract "The aim of this study was to perform a systematic review and meta-analysis to assess the safety and efficacy of interventional treatment for Budd-Chiari syndrome (BCS) complicated by Inferior Vena Cava thrombosis (IVCT) patients. We evaluated the published studies on interventional treatment for BCS complicated by IVCT. Meta-analysis was used to calculate the combined effect size and their 95% confidence intervals (CI) based on random effect. The publication bias was assessed by Begg's test. Sixteen studies on interventional treatment for BCS complicated by IVCT patient were selected for meta-analysis, a total of 767 BCS complicated by IVCT patients were included. The combined effect size (95% CI) were 99% (98–100%) for the total successful rate of IVC recanalization, 15% (11–21%) for the rate of IVC restenosis after initial operation, 92.0% (86–97%) for the rate of clinical improvement, 76% (68–84%) for the rate of thrombus clearance and 0.00% (0–1%) for the incidence of pulmonary embolism (PE). Through subgroup meta-analysis about the rate of thrombus clearance, we got the pooled results (95% CI) of individualized treatment strategy (ITS) group and non-individualized treatment strategy (non-ITS) group, were 81% (71–92%) and 73% (63–83%), respectively. The interventional treatment for BCS complicated by IVCT patients is safe and effective with low incidence of PE, high thrombus clearance rate, high technically successful rate, good patency, and high clinical improvement rate. Moreover, subgroup analysis indicated that management based on the type and extent of the thrombus is proposed. El objetivo de este estudio fue realizar una revisión y un metaanálisis sistemáticos para evaluar la seguridad y la eficacia del tratamiento intervencionista en los pacientes con el síndrome de Budd-Chiari (SBC), agravado por trombosis de la vena cava inferior (TVCI). Evaluamos los estudios publicados sobre el tratamiento intervencionista del SBC agravado por TVCI. Se utilizó el metaanálisis para calcular el tamaño del efecto combinado y los intervalos de confianza (IC) del 95%, basados en el efecto aleatorio. El sesgo de publicación se evaluó con la prueba de Begg. Para el metaanálisis se seleccionaron 16 estudios sobre el tratamiento intervencionista de pacientes con SBC agravado por TVCI; se incluyó un total de 767 pacientes con SBC agravado por TVCI. El tamaño del efecto combinado (IC del 95%) fue del 99% (98-100%) para la tasa de éxito global de la recanalización de la vena cava inferior (VCI), un 15% (11-21%) para la tasa de reestenosis de la VCI después de la operación inicial, un 92% (86-97%) para la tasa de mejora clínica, un 76% (68-84%) para la tasa de eliminación de trombos y un 0% (0-1%) para la incidencia de embolia pulmonar. En el metaanálisis de subgrupos de la tasa de eliminación de trombos, los resultados combinados (IC del 95%) para el grupo de estrategia de tratamiento individualizado y el grupo de estrategia de tratamiento no individualizado fueron del 81% (71-92%) y del 73% (63-83%), respectivamente. El tratamiento intervencionista de pacientes con SBC agravado por TVCI es seguro y eficaz, con una baja incidencia de embolia pulmonar, una alta tasa de eliminación de trombos, una alta tasa de éxito técnico, una buena permeabilidad y una tasa elevada de mejora clínica. Además, el análisis de subgrupos reveló que el mejor enfoque es el tratamiento basado en el tipo y la extensión del trombo." @default.
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• W4249262905 date "2021-06-01" @default.
• W4249262905 modified "2023-10-14" @default.
• W4249262905 title "The outcomes of interventional treatment for Budd-Chiari Syndrome complicated by inferior vena cava thrombosis: Systematic review and meta-analysis" @default.
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• W4249262905 doi "https://doi.org/10.1016/j.gastre.2020.06.030" @default.
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