FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4249263610> ?p ?o ?g. }

• W4249263610 abstract "Abstract Background: Aortic stenosis (AS) causes left ventricular (LV) pressure overload, leading to adverse LV remodeling and dysfunction. We examined the impact of severe AS and its consequent increase in LV afterload on myocardial deformation and rotational mechanics by 2-dimensional (2D) and 3-dimensional (3D) speckle-tracking echocardiography. Methods: We prospectively measured various strain parameters in 168 patients (42% female, mean age 72±12 years) with severe AS and LV ejection fraction (EF) ≥50%, and compared them to normal values found in literature. 2D and 3D images were analyzed for global longitudinal strain (GLS), global circumferential strain (GCS), global radial strain (GRS), basal rotation, apical rotation, and peak systolic twist. We further assessed the degree of concordance between 2D and 3D strain, and examined their association with measures of LV preload and afterload. Results: Patients with severe AS exhibited significantly lower GLS and GRS but higher GCS, apical rotation, and twist by 2D and 3D echocardiography compared with published normal values (P=0.003 for 3D twist,P<0.001 for all others). There was modest agreement between 2D and 3D GLS measurements (concordance correlation coefficient 0.49, 95% confidence interval 0.39-0.57). GLS was modestly correlated with valvulo-arterial impedance, a measure of LV afterload (r=0.34, p<0.001 for 2D and r=0.23, p=0.003 for 3D). Conclusion: Patients with severe AS demonstrate lower-than-normal GLS and GRS as a result of increased afterload but appear to compensate with higher-than-normal GCS, apical rotation, and twist in order to maintain a preserved LVEF. Our study provides, to our knowledge, the most comprehensive analysis to date of myocardial deformation and rotational mechanics by 2D and 3D speckle-tracking echocardiography in patients with severe AS and preserved LVEF." @default.
• W4249263610 created "2022-05-12" @default.
• W4249263610 creator A5000044916 @default.
• W4249263610 creator A5000158247 @default.
• W4249263610 creator A5010897991 @default.
• W4249263610 creator A5026143817 @default.
• W4249263610 creator A5029815013 @default.
• W4249263610 creator A5030091790 @default.
• W4249263610 creator A5050028396 @default.
• W4249263610 creator A5069143725 @default.
• W4249263610 creator A5069980045 @default.
• W4249263610 creator A5071756871 @default.
• W4249263610 creator A5073025689 @default.
• W4249263610 creator A5081777517 @default.
• W4249263610 creator A5086970664 @default.
• W4249263610 date "2019-12-12" @default.
• W4249263610 modified "2023-09-27" @default.
• W4249263610 title "Dissecting Myocardial Mechanics in Patients with Severe Aortic Stenosis: 2-Dimensional vs 3-Dimensional-Speckle Tracking Echocardiography" @default.
• W4249263610 cites W1518594242 @default.
• W4249263610 cites W1978847400 @default.
• W4249263610 cites W1982321891 @default.
• W4249263610 cites W1994976809 @default.
• W4249263610 cites W2020845700 @default.
• W4249263610 cites W2022058066 @default.
• W4249263610 cites W2030316655 @default.
• W4249263610 cites W2031249707 @default.
• W4249263610 cites W2037402552 @default.
• W4249263610 cites W2054649276 @default.
• W4249263610 cites W2055649417 @default.
• W4249263610 cites W2057713302 @default.
• W4249263610 cites W2067561320 @default.
• W4249263610 cites W2076418140 @default.
• W4249263610 cites W2081440227 @default.
• W4249263610 cites W2081964645 @default.
• W4249263610 cites W2085786241 @default.
• W4249263610 cites W2087600429 @default.
• W4249263610 cites W2089277056 @default.
• W4249263610 cites W2094400009 @default.
• W4249263610 cites W2103819289 @default.
• W4249263610 cites W2104803428 @default.
• W4249263610 cites W2109832896 @default.
• W4249263610 cites W2123413271 @default.
• W4249263610 cites W2124624517 @default.
• W4249263610 cites W2131916402 @default.
• W4249263610 cites W2138131353 @default.
• W4249263610 cites W2139941951 @default.
• W4249263610 cites W2154939507 @default.
• W4249263610 cites W2155757264 @default.
• W4249263610 cites W2157264444 @default.
• W4249263610 cites W2160099993 @default.
• W4249263610 cites W2186188224 @default.
• W4249263610 cites W2271883565 @default.
• W4249263610 cites W2410518596 @default.
• W4249263610 cites W2548762833 @default.
• W4249263610 cites W2580834481 @default.
• W4249263610 cites W2887245507 @default.
• W4249263610 cites W2889815369 @default.
• W4249263610 cites W2946080087 @default.
• W4249263610 cites W2980089630 @default.
• W4249263610 doi "https://doi.org/10.21203/rs.2.14188/v2" @default.
• W4249263610 hasPublicationYear "2019" @default.
• W4249263610 type Work @default.
• W4249263610 citedByCount "0" @default.
• W4249263610 crossrefType "posted-content" @default.
• W4249263610 hasAuthorship W4249263610A5000044916 @default.
• W4249263610 hasAuthorship W4249263610A5000158247 @default.
• W4249263610 hasAuthorship W4249263610A5010897991 @default.
• W4249263610 hasAuthorship W4249263610A5026143817 @default.
• W4249263610 hasAuthorship W4249263610A5029815013 @default.
• W4249263610 hasAuthorship W4249263610A5030091790 @default.
• W4249263610 hasAuthorship W4249263610A5050028396 @default.
• W4249263610 hasAuthorship W4249263610A5069143725 @default.
• W4249263610 hasAuthorship W4249263610A5069980045 @default.
• W4249263610 hasAuthorship W4249263610A5071756871 @default.
• W4249263610 hasAuthorship W4249263610A5073025689 @default.
• W4249263610 hasAuthorship W4249263610A5081777517 @default.
• W4249263610 hasAuthorship W4249263610A5086970664 @default.
• W4249263610 hasBestOaLocation W42492636101 @default.
• W4249263610 hasConcept C105795698 @default.
• W4249263610 hasConcept C123576724 @default.
• W4249263610 hasConcept C126322002 @default.
• W4249263610 hasConcept C164705383 @default.
• W4249263610 hasConcept C178853913 @default.
• W4249263610 hasConcept C2524010 @default.
• W4249263610 hasConcept C2776196297 @default.
• W4249263610 hasConcept C2778198053 @default.
• W4249263610 hasConcept C2778271984 @default.
• W4249263610 hasConcept C2778296771 @default.
• W4249263610 hasConcept C2780007028 @default.
• W4249263610 hasConcept C2780714102 @default.
• W4249263610 hasConcept C2781059462 @default.
• W4249263610 hasConcept C2781414266 @default.
• W4249263610 hasConcept C3018791406 @default.
• W4249263610 hasConcept C33923547 @default.
• W4249263610 hasConcept C48277249 @default.
• W4249263610 hasConcept C71924100 @default.
• W4249263610 hasConcept C78085059 @default.
• W4249263610 hasConceptScore W4249263610C105795698 @default.
• W4249263610 hasConceptScore W4249263610C123576724 @default.
• W4249263610 hasConceptScore W4249263610C126322002 @default.

• next