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- W4249282364 abstract "An unusual disease, mastocytosis challenges the pathologist with a variety of morphologic appearances and heterogeneous clinical presentations ranging from skin manifestations (pruritus, urticaria, dermatographism) to systemic signs and symptoms indicative of mast cell mediator release, including flushing, hypotension, headache, and anaphylaxis among others. In this article, we focus on recognizing the cytology, histopathology, clinical features, and prognostic implications of systemic mastocytosis, a clonal and neoplastic mast cell proliferation infiltrating extracutaneous organ(s) with or without skin involvement. Diagnostic pitfalls are reviewed with ancillary studies to help unmask the mast cell and exclude morphologic mimics." @default.
- W4249282364 created "2022-05-12" @default.
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- W4249282364 date "2010-12-01" @default.
- W4249282364 modified "2023-10-18" @default.
- W4249282364 title "Systemic Mastocytosis" @default.
- W4249282364 doi "https://doi.org/10.1016/j.path.2010.09.003" @default.
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