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- W4249477498 abstract "The aim of this study is to investigate the expressions of p16 and HPV16/18(E6) in oral lichen planus (OLP) and malignant transformed OLP (MT-OLP).The expression of p16 and HPV16/18(E6) in 40 cases of OLP and 6 MT-OLP was assessed by immunohistochemical staining. Twenty four cases of normal oral mucosa were used as controls.Compared to normal oral mucosa, the expression of p16 and HPV16/18(E6) protein increased in OLP and MT-OLP. And there was a correlation between p16 expression and HPV infection in OLP and OLP malignant lesions (p < 0.0001).The expression of p16 protein might predict HPV16/18 infection in OLP. And HPV16/18(E6) infection might contribute to OLP malignant transformation." @default.
- W4249477498 created "2022-05-12" @default.
- W4249477498 date "2016-11-01" @default.
- W4249477498 modified "2023-09-30" @default.
- W4249477498 title "P16" @default.
- W4249477498 doi "https://doi.org/10.1016/j.freeradbiomed.2016.10.032" @default.
- W4249477498 hasPublicationYear "2016" @default.
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