Matches in SemOpenAlex for { <https://semopenalex.org/work/W4249701940> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W4249701940 endingPage "126" @default.
- W4249701940 startingPage "123" @default.
- W4249701940 abstract "Cyclocondensation of two disubstituted 6-aminopyrimidines 11 and 12 with 1-benzyl-3-hydroxymethylene-4-piperidone afforded new tricyclic, linear disubstituted 6,7,8,9-tetrahydropyrimido[4,5-b][1,6]naphthyridines 4 and 5 respectively. Similar cyclocondensation of 11 with 1-benzoyl-1,2,3,6-tetrahydropyridine-5-carboxalde-hyde gave the corresponding benzoylated tetrahydropyrimido[4,5-b][1,6]naphthyridine 6. Debenzoylation of 6 afforded 7. 1-Benzyl-3-aminomethylene-4-piperidone when cyclocondensed with 11 also afforded 4. The linear structures were established by 1H nmr and 13C nmr. The growth of leukemia L1210 cells in culture was inhibited about 50% by 4,5,6 and 7 at 100 μM." @default.
- W4249701940 created "2022-05-12" @default.
- W4249701940 creator A5052708209 @default.
- W4249701940 creator A5081478984 @default.
- W4249701940 date "1987-01-01" @default.
- W4249701940 modified "2023-09-26" @default.
- W4249701940 title "Synthesis of some substituted tetrahydropyrimido[4,5-<i>b</i>][1,6]naphthyridines as potential antitumor agents" @default.
- W4249701940 cites W1968035791 @default.
- W4249701940 cites W2055423533 @default.
- W4249701940 cites W2067570224 @default.
- W4249701940 cites W2069771713 @default.
- W4249701940 cites W2076131200 @default.
- W4249701940 cites W2083467467 @default.
- W4249701940 cites W2086932754 @default.
- W4249701940 cites W2164045961 @default.
- W4249701940 cites W2315845902 @default.
- W4249701940 cites W2326954627 @default.
- W4249701940 cites W2330532551 @default.
- W4249701940 cites W2950129816 @default.
- W4249701940 doi "https://doi.org/10.1002/jhet.5570240125" @default.
- W4249701940 hasPublicationYear "1987" @default.
- W4249701940 type Work @default.
- W4249701940 citedByCount "12" @default.
- W4249701940 countsByYear W42497019402021 @default.
- W4249701940 crossrefType "journal-article" @default.
- W4249701940 hasAuthorship W4249701940A5052708209 @default.
- W4249701940 hasAuthorship W4249701940A5081478984 @default.
- W4249701940 hasConcept C163111631 @default.
- W4249701940 hasConcept C185592680 @default.
- W4249701940 hasConcept C2781081902 @default.
- W4249701940 hasConcept C71240020 @default.
- W4249701940 hasConceptScore W4249701940C163111631 @default.
- W4249701940 hasConceptScore W4249701940C185592680 @default.
- W4249701940 hasConceptScore W4249701940C2781081902 @default.
- W4249701940 hasConceptScore W4249701940C71240020 @default.
- W4249701940 hasIssue "1" @default.
- W4249701940 hasLocation W42497019401 @default.
- W4249701940 hasOpenAccess W4249701940 @default.
- W4249701940 hasPrimaryLocation W42497019401 @default.
- W4249701940 hasRelatedWork W2002352285 @default.
- W4249701940 hasRelatedWork W2047643436 @default.
- W4249701940 hasRelatedWork W2048834570 @default.
- W4249701940 hasRelatedWork W2063453877 @default.
- W4249701940 hasRelatedWork W2313293413 @default.
- W4249701940 hasRelatedWork W2322806991 @default.
- W4249701940 hasRelatedWork W2951109342 @default.
- W4249701940 hasRelatedWork W2951585141 @default.
- W4249701940 hasRelatedWork W2952778133 @default.
- W4249701940 hasRelatedWork W4285090289 @default.
- W4249701940 hasVolume "24" @default.
- W4249701940 isParatext "false" @default.
- W4249701940 isRetracted "false" @default.
- W4249701940 workType "article" @default.