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- W4249705430 abstract "Abstract Backgrounds: IL-6 is associated with the severity of mycoplasma pneumoniae pneumonia (MPP). But the relationship of IL-27 and MPP was unknown. Methods: 98 patients with MPP younger than 14 years old were enrolled in this study and divided into mild cases and severe cases by severity of disease, MP single infection group and MP mixed infection group by MP mixed-infection types, and low MP DNA loads group and high MP DNA loads group by MP DNA loads respectively. 15 children with foreign bronchus bodies were also enrolled as control. The levels of IL-6 and IL-27 in BALFs collected from these children were assayed by ELISA. Results: There were significant differences in the levels of IL-6 in BALFs from patients between 3 patient groups, respectively ( P ﹤0.05). Compared with the levels of IL-6 in BALFs from control, the levels of IL-6 in BALFs from the 5 groups were significantly higher ( P ﹤0.05) except that from low MP DNA loads group. The levels of IL-27 in BALFs from MP mixed infection group were significantly higher than those from MP single infection group and control( P ﹤0.05). Conclusion: IL-6 was firmly associated with MPP and had potential application in clinical practice while IL-27 was not associated with MP infection." @default.
- W4249705430 created "2022-05-12" @default.
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- W4249705430 date "2019-10-09" @default.
- W4249705430 modified "2023-09-26" @default.
- W4249705430 title "The clinical significance of IL-6s and IL-27s in Bronchoalveolar lavage fluids from children with mycoplasma pneumoniae pneumonia" @default.
- W4249705430 doi "https://doi.org/10.21203/rs.2.15861/v1" @default.
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