Matches in SemOpenAlex for { <https://semopenalex.org/work/W4249726269> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W4249726269 abstract "Abstract Background To compare the efficacy of the combination of transarterial chemoembolization (TACE) and iodine 125 seeds implantation (TACE-Iodine 125) with the combination of TACE and radiofrequency ablation (RFA) in the treatment of patients with early and intermediate hepatocellular carcinoma (HCC). Methods The study included 134 patients diagnosed with early and intermediate HCC from January 1, 2014, to May 31, 2018. Among them, 47 patients were treated with TACE-Iodine 125, and 87 with TACE-RFA and the efficacy of both treatments was analyzed. To reduced selective bias, propensity score matching (PSM) was used to compare the outcomes of the treatments. Results In the absence of PSM, the median overall survival (OS) and progression-free survival (PFS) of the TACE-RFA group were slightly longer than those of the TACE-Iodine 125 group (OS: 42 months vs. 37 months; PFS: 18 months vs. 15 months). However, there was no significant difference in median OS, PFS, and the objective response rate (ORR) between the two groups (P>0.05). After adjusted for age, gender, liver resection, Child-Pugh class, Barcelona Clinic Liver Cancer (BCLC) stage and Alpha-fetoprotein (AFP), TACE-Iodine 125 treatment was not associated with a significant increasing in risk of death (HR: 0.725; 95%CI: 0.423,1.241, P=0.241) and recurrence (HR: 1.008; 95%CI: 0.666,1.526, P=0.969). After PSM, 47 patient pairs were generated, and there was no significant difference in median OS and PFS between the two groups. Conclusions The combination of TACE and iodine 125 seeds implantation may represent an effective treatment for patients with early and intermediate HCC." @default.
- W4249726269 created "2022-05-12" @default.
- W4249726269 creator A5005273133 @default.
- W4249726269 creator A5009097695 @default.
- W4249726269 creator A5012816472 @default.
- W4249726269 creator A5027271655 @default.
- W4249726269 creator A5030938471 @default.
- W4249726269 creator A5037195175 @default.
- W4249726269 creator A5038847528 @default.
- W4249726269 creator A5041054587 @default.
- W4249726269 creator A5043461956 @default.
- W4249726269 date "2020-01-28" @default.
- W4249726269 modified "2023-09-27" @default.
- W4249726269 title "Transarterial Chemoembolization Combined with Iodine 125 Seeds Versus Transarterial Chemoembolization Combined with Radiofrequency Ablation in the Treatment of Early and Intermediate Hepatocellular Carcinoma" @default.
- W4249726269 doi "https://doi.org/10.21203/rs.2.21964/v1" @default.
- W4249726269 hasPublicationYear "2020" @default.
- W4249726269 type Work @default.
- W4249726269 citedByCount "0" @default.
- W4249726269 crossrefType "posted-content" @default.
- W4249726269 hasAuthorship W4249726269A5005273133 @default.
- W4249726269 hasAuthorship W4249726269A5009097695 @default.
- W4249726269 hasAuthorship W4249726269A5012816472 @default.
- W4249726269 hasAuthorship W4249726269A5027271655 @default.
- W4249726269 hasAuthorship W4249726269A5030938471 @default.
- W4249726269 hasAuthorship W4249726269A5037195175 @default.
- W4249726269 hasAuthorship W4249726269A5038847528 @default.
- W4249726269 hasAuthorship W4249726269A5041054587 @default.
- W4249726269 hasAuthorship W4249726269A5043461956 @default.
- W4249726269 hasBestOaLocation W42497262692 @default.
- W4249726269 hasConcept C126322002 @default.
- W4249726269 hasConcept C146357865 @default.
- W4249726269 hasConcept C151730666 @default.
- W4249726269 hasConcept C167135981 @default.
- W4249726269 hasConcept C17923572 @default.
- W4249726269 hasConcept C191897082 @default.
- W4249726269 hasConcept C192562407 @default.
- W4249726269 hasConcept C2776231280 @default.
- W4249726269 hasConcept C2777377203 @default.
- W4249726269 hasConcept C2778019345 @default.
- W4249726269 hasConcept C2778902805 @default.
- W4249726269 hasConcept C3019894029 @default.
- W4249726269 hasConcept C539932907 @default.
- W4249726269 hasConcept C71924100 @default.
- W4249726269 hasConcept C86803240 @default.
- W4249726269 hasConcept C90924648 @default.
- W4249726269 hasConceptScore W4249726269C126322002 @default.
- W4249726269 hasConceptScore W4249726269C146357865 @default.
- W4249726269 hasConceptScore W4249726269C151730666 @default.
- W4249726269 hasConceptScore W4249726269C167135981 @default.
- W4249726269 hasConceptScore W4249726269C17923572 @default.
- W4249726269 hasConceptScore W4249726269C191897082 @default.
- W4249726269 hasConceptScore W4249726269C192562407 @default.
- W4249726269 hasConceptScore W4249726269C2776231280 @default.
- W4249726269 hasConceptScore W4249726269C2777377203 @default.
- W4249726269 hasConceptScore W4249726269C2778019345 @default.
- W4249726269 hasConceptScore W4249726269C2778902805 @default.
- W4249726269 hasConceptScore W4249726269C3019894029 @default.
- W4249726269 hasConceptScore W4249726269C539932907 @default.
- W4249726269 hasConceptScore W4249726269C71924100 @default.
- W4249726269 hasConceptScore W4249726269C86803240 @default.
- W4249726269 hasConceptScore W4249726269C90924648 @default.
- W4249726269 hasLocation W42497262691 @default.
- W4249726269 hasLocation W42497262692 @default.
- W4249726269 hasOpenAccess W4249726269 @default.
- W4249726269 hasPrimaryLocation W42497262691 @default.
- W4249726269 hasRelatedWork W10327424 @default.
- W4249726269 hasRelatedWork W10358853 @default.
- W4249726269 hasRelatedWork W11316963 @default.
- W4249726269 hasRelatedWork W1233562 @default.
- W4249726269 hasRelatedWork W13948068 @default.
- W4249726269 hasRelatedWork W17623510 @default.
- W4249726269 hasRelatedWork W2997061 @default.
- W4249726269 hasRelatedWork W5612486 @default.
- W4249726269 hasRelatedWork W7743602 @default.
- W4249726269 hasRelatedWork W8872191 @default.
- W4249726269 isParatext "false" @default.
- W4249726269 isRetracted "false" @default.
- W4249726269 workType "article" @default.