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- W4249737868 abstract "Frankensteins Peptid: Bei der Pfropfung der Bindedomäne aus dem Miniprotein Min-23 in das Gerüst des Sonnenblumen-Trypsininhibitor(SFTI-I)-Peptids (siehe Schema) bleiben dessen In-vitro- und In-vivo-Bindungsspezifität und Proteolysebeständigkeit erhalten. Das kombinierte Peptid erwies sich als tumorspezifisch mit einer guten Bindungsaffinität für das Delta-artige Ligand-4-Protein (Dll4). Die Verwendung von SFTI-I als Peptidgerüst ist ideal für die Leitstrukturentwicklung." @default.
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- W4249737868 date "2012-11-13" @default.
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- W4249737868 title "Combination of Phage Display and Molecular Grafting Generates Highly Specific Tumor-Targeting Miniproteins" @default.
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- W4249737868 doi "https://doi.org/10.1002/ange.201203857" @default.
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