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- W4249787726 abstract "Background and Objective: Central precocious puberty (CPP) is defined as the onset of breast development (thelarche) before age 8 years in girls and testicular development (gonadarche) before age 9 years in boys due to early activation of the hypothalamic-pituitary-gonadal (HPG) axis. In most cases, the exact etiology of CPP is not known. In girls, CPP is commonly idiopathic. In contrast, CPP in boys is likely pathologic. Gonadotropin-releasing hormone agonists (GnRHa) are the gold standard treatment of CPP, with the main objective to halt the pubertal progression and delay skeletal maturation preserving final adult height. In this narrative review, our focus is to review the treatment outcomes of GnRHa on adult height, reproductive function, BMI, cardiovascular and bone health in patients with CPP after brief description of CPP, etiology, and diagnosis." @default.
- W4249787726 created "2022-05-12" @default.
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- W4249787726 date "2023-05-01" @default.
- W4249787726 modified "2023-09-27" @default.
- W4249787726 title "A narrative review: treatment outcomes of central precocious puberty (CPP)" @default.
- W4249787726 doi "https://doi.org/10.21037/pm-21-105" @default.
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