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• W4249789020 abstract "Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are oncogenic drivers that occur in a wide range of tumor types. Larotrectinib, a highly selective Food and Drug Administration and European Medicines Agency approved TRK inhibitor, demonstrated an objective response rate (ORR) of 79% and a median duration of response (DoR) of 35 months across multiple cancers (Hong et al. Lancet Oncol 2020). Here we report updated data for patients with TRK fusion lung cancer assessed by independent review committee (IRC) and investigators (INV)." @default.
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• W4249789020 date "2021-03-01" @default.
• W4249789020 modified "2023-10-01" @default.
• W4249789020 title "MA11.09 Efficacy and Safety of Larotrectinib in Patients with Tropomyosin Receptor Kinase (TRK) Fusion Lung Cancer" @default.
• W4249789020 doi "https://doi.org/10.1016/j.jtho.2021.01.253" @default.
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