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- W4249793669 abstract "The pathology of MS consists of areas of focal demyelination, known as plaques or lesions, characterized by inflammation, gliosis, and relative axonal preservation. Recent neuropathological studies have established that white matter lesions are heterogenous with respect to the targets of injury and mechanisms of demyelination, highlighting the need for the identification of surrogate clinical and/or paraclinical markers that would correlate with immunopatterns in the general MS population and for the design of novel therapeutic strategies specifically tailored to each immunopattern. Recent neuropathological studies have also shown the cortex is an early target of the MS disease process, and that inflammatory cortical demyelination may be driven by meningeal inflammation." @default.
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- W4249793669 date "2017-03-01" @default.
- W4249793669 modified "2023-09-26" @default.
- W4249793669 title "Multiple Sclerosis: Pathology" @default.
- W4249793669 doi "https://doi.org/10.1093/med/9780199937837.003.0081" @default.
- W4249793669 hasPublicationYear "2017" @default.
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