FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4249794612> ?p ?o ?g. }

• W4249794612 endingPage "536" @default.
• W4249794612 startingPage "528" @default.
• W4249794612 abstract "ObjectivesTranscatheter aortic valve replacement has proven successful in treating intermediate-risk, high-risk, and inoperable patients with severe aortic stenosis. Third-generation, balloon-expandable transcatheter aortic valves were developed with an outer sealing skirt to reduce paravalvular leakage. As transcatheter aortic valve replacement use expands, long-term durability questions remain. Valve design influences durability, where regions of increased leaflet stress are vulnerable to early degeneration. However, third-generation transcatheter aortic valve stresses are unknown. Our goals were to determine the stent and leaflet stresses of third-generation, balloon-expandable transcatheter aortic valves.MethodsThe commercial 26-mm Edwards SAPIEN 3 valve (Edwards Lifesciences, Inc, Irvine, Calif) underwent high-resolution micro-computed tomography scanning to develop a precise 3-dimensional geometric mesh of the stent and valve. Leaflet material properties were obtained from surgical bioprostheses, and stent material properties were based on cobalt-chromium. Simulations of systemic pressure loading were performed, and stress was calculated using finite element analyses.ResultsAt diastole, maximum and minimum principal stresses on transcatheter aortic valve leaflets were 2.7 MPa and −0.47 MPa, respectively. Peak leaflet stresses were observed at upper leaflet commissures, at their connection to the stent. Maximum and minimum principal stresses for the stent were 38.2 MPa and −44.4 MPa, respectively, at 80 mm Hg and were located just below the commissural stent.ConclusionsStress analysis of the 26-mm SAPIEN 3 valve using exact geometry from high-resolution scans demonstrated that peak stresses for both transcatheter aortic valve stent and leaflets were present at commissural tips where leaflets were attached. These regions would be most likely to initiate degeneration. The Dacron skirt had minimal effect on stresses on leaflets and stent." @default.
• W4249794612 created "2022-05-12" @default.
• W4249794612 creator A5005515511 @default.
• W4249794612 creator A5007057892 @default.
• W4249794612 creator A5032700450 @default.
• W4249794612 creator A5039350108 @default.
• W4249794612 creator A5049233519 @default.
• W4249794612 creator A5051421749 @default.
• W4249794612 creator A5061220352 @default.
• W4249794612 creator A5067922544 @default.
• W4249794612 date "2019-02-01" @default.
• W4249794612 modified "2023-10-14" @default.
• W4249794612 title "Stent and leaflet stresses in 26-mm, third-generation, balloon-expandable transcatheter aortic valve" @default.
• W4249794612 cites W1580797149 @default.
• W4249794612 cites W1644216083 @default.
• W4249794612 cites W1963927777 @default.
• W4249794612 cites W1970267065 @default.
• W4249794612 cites W1973087163 @default.
• W4249794612 cites W1990247523 @default.
• W4249794612 cites W2021068519 @default.
• W4249794612 cites W2053088455 @default.
• W4249794612 cites W2067905792 @default.
• W4249794612 cites W2083346116 @default.
• W4249794612 cites W2101780235 @default.
• W4249794612 cites W2109553540 @default.
• W4249794612 cites W2144067446 @default.
• W4249794612 cites W2162079984 @default.
• W4249794612 cites W2165754900 @default.
• W4249794612 cites W2318441640 @default.
• W4249794612 cites W2324073140 @default.
• W4249794612 cites W2324520536 @default.
• W4249794612 cites W2461037610 @default.
• W4249794612 cites W2472486038 @default.
• W4249794612 cites W2561214000 @default.
• W4249794612 cites W2562791314 @default.
• W4249794612 cites W2596188051 @default.
• W4249794612 cites W2607374947 @default.
• W4249794612 cites W2625889445 @default.
• W4249794612 cites W2748980750 @default.
• W4249794612 cites W2785020011 @default.
• W4249794612 cites W630382629 @default.
• W4249794612 cites W751610616 @default.
• W4249794612 doi "https://doi.org/10.1016/j.jtcvs.2018.04.115" @default.
• W4249794612 hasPublicationYear "2019" @default.
• W4249794612 type Work @default.
• W4249794612 citedByCount "16" @default.
• W4249794612 countsByYear W42497946122019 @default.
• W4249794612 countsByYear W42497946122020 @default.
• W4249794612 countsByYear W42497946122021 @default.
• W4249794612 countsByYear W42497946122022 @default.
• W4249794612 countsByYear W42497946122023 @default.
• W4249794612 crossrefType "journal-article" @default.
• W4249794612 hasAuthorship W4249794612A5005515511 @default.
• W4249794612 hasAuthorship W4249794612A5007057892 @default.
• W4249794612 hasAuthorship W4249794612A5032700450 @default.
• W4249794612 hasAuthorship W4249794612A5039350108 @default.
• W4249794612 hasAuthorship W4249794612A5049233519 @default.
• W4249794612 hasAuthorship W4249794612A5051421749 @default.
• W4249794612 hasAuthorship W4249794612A5061220352 @default.
• W4249794612 hasAuthorship W4249794612A5067922544 @default.
• W4249794612 hasBestOaLocation W42497946121 @default.
• W4249794612 hasConcept C126838900 @default.
• W4249794612 hasConcept C139059822 @default.
• W4249794612 hasConcept C141071460 @default.
• W4249794612 hasConcept C164705383 @default.
• W4249794612 hasConcept C2776229121 @default.
• W4249794612 hasConcept C2778583881 @default.
• W4249794612 hasConcept C2780007028 @default.
• W4249794612 hasConcept C2780026749 @default.
• W4249794612 hasConcept C2780714102 @default.
• W4249794612 hasConcept C71924100 @default.
• W4249794612 hasConceptScore W4249794612C126838900 @default.
• W4249794612 hasConceptScore W4249794612C139059822 @default.
• W4249794612 hasConceptScore W4249794612C141071460 @default.
• W4249794612 hasConceptScore W4249794612C164705383 @default.
• W4249794612 hasConceptScore W4249794612C2776229121 @default.
• W4249794612 hasConceptScore W4249794612C2778583881 @default.
• W4249794612 hasConceptScore W4249794612C2780007028 @default.
• W4249794612 hasConceptScore W4249794612C2780026749 @default.
• W4249794612 hasConceptScore W4249794612C2780714102 @default.
• W4249794612 hasConceptScore W4249794612C71924100 @default.
• W4249794612 hasIssue "2" @default.
• W4249794612 hasLocation W42497946121 @default.
• W4249794612 hasLocation W42497946122 @default.
• W4249794612 hasLocation W42497946123 @default.
• W4249794612 hasOpenAccess W4249794612 @default.
• W4249794612 hasPrimaryLocation W42497946121 @default.
• W4249794612 hasRelatedWork W1968935734 @default.
• W4249794612 hasRelatedWork W1971222746 @default.
• W4249794612 hasRelatedWork W1975550642 @default.
• W4249794612 hasRelatedWork W2021068519 @default.
• W4249794612 hasRelatedWork W2142963869 @default.
• W4249794612 hasRelatedWork W2724263304 @default.
• W4249794612 hasRelatedWork W2740587233 @default.
• W4249794612 hasRelatedWork W3158657410 @default.
• W4249794612 hasRelatedWork W4246097017 @default.
• W4249794612 hasRelatedWork W2740768811 @default.
• W4249794612 hasVolume "157" @default.

• next