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- W4249888961 abstract "Experiments show that upon traumatic injury the composition of mesenteric lymph changes such that it initiates an immune response that can ultimately result in multiple organ dysfunction syndrome (MODS). To identify candidate protein mediators of this process we carried out a quantitative proteomic study on mesenteric lymph from a well characterized rat shock model. We analyzed three animals using analytical 2D differential gel electrophoresis. Intra-animal variation for the majority of protein spots was minor. Functional clustering of proteins revealed changes arising from several global classes that give novel insight into fundamental mechanisms of MODS. Mass spectrometry based proteomic analysis of proteins in mesenteric lymph can effectively be used to identify candidate mediators and loss of protective agents in shock models." @default.
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- W4249888961 date "2010-11-27" @default.
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- W4249888961 title "Proteomic Profiling of the Mesenteric Lymph After Hemorrhagic Shock: Differential Gel Electrophoresis and Mass Spectrometry Analysis" @default.
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- W4249888961 doi "https://doi.org/10.1007/s12014-010-9061-0" @default.
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