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- W4249889795 abstract "Dopaminergic (DA) neurons in the mammalian midbrain region are preferentially lost in Parkinson’s disease (PD), the second most common neurodegenerative disease. The DA neurons are generated through the interactions of multiple extrinsic and intrinsic factors during embryogenesis. The molecular identities and the mechanisms of action of an increasing number of such factors have been elucidated. Many of the same factors have been successfully used to induce differentiation of DA neurons in vitro from embryonic or neural stem cells. These advances promise to contribute the future discovery of new medicines for PD treatment." @default.
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- W4249889795 date "2009-01-01" @default.
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- W4249889795 title "Dopaminergic Differentiation" @default.
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- W4249889795 doi "https://doi.org/10.1016/b978-008045046-9.01037-8" @default.
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