Matches in SemOpenAlex for { <https://semopenalex.org/work/W4250041034> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4250041034 abstract "Abstract Background: The number of confirmed COVID-19 cases divided by population size is used as a coarse measurement for the burden of disease in a population. However, this fraction depends heavily on the sampling intensity and the various test criteria used in different jurisdictions, and many sources indicate that a large fraction of cases tend to go undetected. Methods: Estimates of the true prevalence of COVID-19 in a population can be made by random sampling and pooling of RT-PCR tests. Here I use simulations to explore how experiment sample size and degrees of sample pooling impact precision of prevalence estimates and potential for minimizing the total number of tests required to get individual-level diagnostic results. Results: Sample pooling can greatly reduce the total number of tests required for prevalence estimation. In low-prevalence populations, it is theoretically possible to pool hundreds of samples with only marginal loss of precision. Even when the true prevalence is as high as 10% it can be appropriate to pool up to 15 samples. Sample pooling can be particularly beneficial when the test has imperfect specificity by providing more accurate estimates of the prevalence than an equal number of individual-level tests. Conclusion: Sample pooling should be considered in COVID-19 prevalence estimation efforts." @default.
- W4250041034 created "2022-05-12" @default.
- W4250041034 creator A5080805948 @default.
- W4250041034 date "2020-07-10" @default.
- W4250041034 modified "2023-10-18" @default.
- W4250041034 title "COVID-19 prevalence estimation by random sampling in population - Optimal sample pooling under varying assumptions about true prevalence" @default.
- W4250041034 doi "https://doi.org/10.21203/rs.3.rs-32082/v2" @default.
- W4250041034 hasPublicationYear "2020" @default.
- W4250041034 type Work @default.
- W4250041034 citedByCount "0" @default.
- W4250041034 crossrefType "posted-content" @default.
- W4250041034 hasAuthorship W4250041034A5080805948 @default.
- W4250041034 hasBestOaLocation W42500410341 @default.
- W4250041034 hasConcept C105795698 @default.
- W4250041034 hasConcept C106131492 @default.
- W4250041034 hasConcept C129848803 @default.
- W4250041034 hasConcept C140779682 @default.
- W4250041034 hasConcept C142724271 @default.
- W4250041034 hasConcept C149629883 @default.
- W4250041034 hasConcept C149782125 @default.
- W4250041034 hasConcept C154945302 @default.
- W4250041034 hasConcept C162324750 @default.
- W4250041034 hasConcept C178790620 @default.
- W4250041034 hasConcept C185592680 @default.
- W4250041034 hasConcept C187736073 @default.
- W4250041034 hasConcept C198531522 @default.
- W4250041034 hasConcept C2779134260 @default.
- W4250041034 hasConcept C2908647359 @default.
- W4250041034 hasConcept C3008058167 @default.
- W4250041034 hasConcept C31972630 @default.
- W4250041034 hasConcept C33923547 @default.
- W4250041034 hasConcept C41008148 @default.
- W4250041034 hasConcept C43617362 @default.
- W4250041034 hasConcept C524204448 @default.
- W4250041034 hasConcept C70437156 @default.
- W4250041034 hasConcept C71924100 @default.
- W4250041034 hasConcept C96250715 @default.
- W4250041034 hasConcept C99454951 @default.
- W4250041034 hasConceptScore W4250041034C105795698 @default.
- W4250041034 hasConceptScore W4250041034C106131492 @default.
- W4250041034 hasConceptScore W4250041034C129848803 @default.
- W4250041034 hasConceptScore W4250041034C140779682 @default.
- W4250041034 hasConceptScore W4250041034C142724271 @default.
- W4250041034 hasConceptScore W4250041034C149629883 @default.
- W4250041034 hasConceptScore W4250041034C149782125 @default.
- W4250041034 hasConceptScore W4250041034C154945302 @default.
- W4250041034 hasConceptScore W4250041034C162324750 @default.
- W4250041034 hasConceptScore W4250041034C178790620 @default.
- W4250041034 hasConceptScore W4250041034C185592680 @default.
- W4250041034 hasConceptScore W4250041034C187736073 @default.
- W4250041034 hasConceptScore W4250041034C198531522 @default.
- W4250041034 hasConceptScore W4250041034C2779134260 @default.
- W4250041034 hasConceptScore W4250041034C2908647359 @default.
- W4250041034 hasConceptScore W4250041034C3008058167 @default.
- W4250041034 hasConceptScore W4250041034C31972630 @default.
- W4250041034 hasConceptScore W4250041034C33923547 @default.
- W4250041034 hasConceptScore W4250041034C41008148 @default.
- W4250041034 hasConceptScore W4250041034C43617362 @default.
- W4250041034 hasConceptScore W4250041034C524204448 @default.
- W4250041034 hasConceptScore W4250041034C70437156 @default.
- W4250041034 hasConceptScore W4250041034C71924100 @default.
- W4250041034 hasConceptScore W4250041034C96250715 @default.
- W4250041034 hasConceptScore W4250041034C99454951 @default.
- W4250041034 hasLocation W42500410341 @default.
- W4250041034 hasLocation W42500410342 @default.
- W4250041034 hasOpenAccess W4250041034 @default.
- W4250041034 hasPrimaryLocation W42500410341 @default.
- W4250041034 hasRelatedWork W104619080 @default.
- W4250041034 hasRelatedWork W1993731342 @default.
- W4250041034 hasRelatedWork W2144630952 @default.
- W4250041034 hasRelatedWork W2172032168 @default.
- W4250041034 hasRelatedWork W2290081135 @default.
- W4250041034 hasRelatedWork W2989992373 @default.
- W4250041034 hasRelatedWork W3022782703 @default.
- W4250041034 hasRelatedWork W3126132007 @default.
- W4250041034 hasRelatedWork W4308354915 @default.
- W4250041034 hasRelatedWork W4310475903 @default.
- W4250041034 isParatext "false" @default.
- W4250041034 isRetracted "false" @default.
- W4250041034 workType "article" @default.