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- W4250129940 abstract "Background: The ALBI score has been recently proposed to predict prognosis in HCC patients. The aim of the study was to verify the ability of ALBI score to stratify short and long-term outcomes in HCC Child-Pugh A patients undergoing surgery. Methods: A retrospective analysis of 180 Child A patients with HCC who underwent surgery from 2006 to 2016 was carried out. The patients were further classified according to the ALBI score. Results: A total of 124 (68.9%) were ALBI-1 (good liver function) and 56 (31.1%) were ALBI-2 (less good liver function). Major hepatectomy was performed in 43 (23.9%) patients. ALBI-2 patients had a higher rate of liver related morbidity compared with ALBI-1: liver failure in 10.7% vs. 2.4% (p=0.027) and ascites in 28.6% vs. 13.7% (p=0.016), respectively. ALBI-1 and ALBI-2 patients had a 5-years OS rate of 55.7% and 35.3%, respectively (p=0.004). Other factors related with OS were BCLC (p< 0.001), AFP >200 ng/mL (p=0.008), size of tumor>10cm (p<0.001), multiple nodules (p=0.001), absence of peritumoral capsula (p=0.028), vascular invasion (p< 0.001). At the multivariate analysis ALBI score (p=0.036), multiple nodules (p=0.014) and size of tumor >10cm (p<0.001) confirmed to be independent prognostic factors. Conclusion: The ALBI score is a simple tool to stratify the liver related morbidity in Child-Pugh A HCC patients undergoing surgery. Moreover, it efficiently predicts the long-term survival and it may be considered in the treatment allocation." @default.
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- W4250129940 date "2019-01-01" @default.
- W4250129940 modified "2023-09-27" @default.
- W4250129940 title "The Albumin-Bilirubin(ALBI) score stratify short-term and long-term outcomes within Child-Pugh A patients undergoing surgery for HCC" @default.
- W4250129940 doi "https://doi.org/10.1016/j.hpb.2019.10.421" @default.
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