Matches in SemOpenAlex for { <https://semopenalex.org/work/W4250171700> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4250171700 endingPage "151" @default.
- W4250171700 startingPage "149" @default.
- W4250171700 abstract "Major depressive disorder (MDD) is one of the most well-known psychiatric disorders, which can be destructive for its damage to people's normal cognitive, emotional and social functions. Personality refers to the unique and stable character of thinking and behavior style of an individual, which has long been thought as a key influence factor for MDD. Although some knowledge about the common neural basic between MDD and personality traits has been acquired, there are few studies exploring dynamic neural mechanism behind them, which changes brain connectivity pattern rapidly to adapt to the environment over time.In this study, the emerging dynamic functional network connectivity (DFNC) method was used in resting-state fMRI data to find the differences between healthy group (N = 107) and MDD group (N = 109) in state-based dynamic measures, and the correlations between these measures and personality traits (extraversion and neuroticism in Eysenck Personality Questionnaire, EPQ) were explored.The results showed that MDD was significantly less than the health control group in dwell time and fraction time of state 4, which was positively correlated with extraversion score and negatively correlated with neuroticism score. Further exploration on state 4 showed that it had low modularity, hyper-connectedness of sensory-related regions and DMN, and weak connections between cortex and subcortical areas, which suggested that the absence of this state in MDD might represent a decrease in activity and positive emotions.We found the dynamic functional connectivity mechanism underlying MDD, confirmed our hypothesis that there existed the interacted relationship between trait, disease and the brain's dynamic characteristic, and suggested some reference for treatment of depression." @default.
- W4250171700 created "2022-05-12" @default.
- W4250171700 date "1996-01-01" @default.
- W4250171700 modified "2023-09-25" @default.
- W4250171700 title "Keyword index" @default.
- W4250171700 doi "https://doi.org/10.1016/s0165-0327(96)90069-5" @default.
- W4250171700 hasPublicationYear "1996" @default.
- W4250171700 type Work @default.
- W4250171700 citedByCount "0" @default.
- W4250171700 crossrefType "journal-article" @default.
- W4250171700 hasConcept C106934330 @default.
- W4250171700 hasConcept C111472728 @default.
- W4250171700 hasConcept C127816348 @default.
- W4250171700 hasConcept C138496976 @default.
- W4250171700 hasConcept C138885662 @default.
- W4250171700 hasConcept C15744967 @default.
- W4250171700 hasConcept C180747234 @default.
- W4250171700 hasConcept C187288502 @default.
- W4250171700 hasConcept C199360897 @default.
- W4250171700 hasConcept C2780051608 @default.
- W4250171700 hasConcept C2780733359 @default.
- W4250171700 hasConcept C2865642 @default.
- W4250171700 hasConcept C41008148 @default.
- W4250171700 hasConcept C70410870 @default.
- W4250171700 hasConcept C77805123 @default.
- W4250171700 hasConcept C89611455 @default.
- W4250171700 hasConcept C94612546 @default.
- W4250171700 hasConceptScore W4250171700C106934330 @default.
- W4250171700 hasConceptScore W4250171700C111472728 @default.
- W4250171700 hasConceptScore W4250171700C127816348 @default.
- W4250171700 hasConceptScore W4250171700C138496976 @default.
- W4250171700 hasConceptScore W4250171700C138885662 @default.
- W4250171700 hasConceptScore W4250171700C15744967 @default.
- W4250171700 hasConceptScore W4250171700C180747234 @default.
- W4250171700 hasConceptScore W4250171700C187288502 @default.
- W4250171700 hasConceptScore W4250171700C199360897 @default.
- W4250171700 hasConceptScore W4250171700C2780051608 @default.
- W4250171700 hasConceptScore W4250171700C2780733359 @default.
- W4250171700 hasConceptScore W4250171700C2865642 @default.
- W4250171700 hasConceptScore W4250171700C41008148 @default.
- W4250171700 hasConceptScore W4250171700C70410870 @default.
- W4250171700 hasConceptScore W4250171700C77805123 @default.
- W4250171700 hasConceptScore W4250171700C89611455 @default.
- W4250171700 hasConceptScore W4250171700C94612546 @default.
- W4250171700 hasIssue "3-4" @default.
- W4250171700 hasLocation W42501717001 @default.
- W4250171700 hasOpenAccess W4250171700 @default.
- W4250171700 hasPrimaryLocation W42501717001 @default.
- W4250171700 hasRelatedWork W1987060531 @default.
- W4250171700 hasRelatedWork W2010801946 @default.
- W4250171700 hasRelatedWork W2027716776 @default.
- W4250171700 hasRelatedWork W2073735673 @default.
- W4250171700 hasRelatedWork W2077863643 @default.
- W4250171700 hasRelatedWork W2157483908 @default.
- W4250171700 hasRelatedWork W4200054511 @default.
- W4250171700 hasRelatedWork W4205329431 @default.
- W4250171700 hasRelatedWork W4226280143 @default.
- W4250171700 hasRelatedWork W4318039504 @default.
- W4250171700 hasVolume "36" @default.
- W4250171700 isParatext "false" @default.
- W4250171700 isRetracted "false" @default.
- W4250171700 workType "article" @default.