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- W4250251081 abstract "Both clinical and experimental data indicate that the pathophysiology of perinatal brain damage is multifactorial and is in many ways distinct from that of adult stroke. Development of the blood–brain barrier (BBB) begins mid-gestation in rodents and continues during the postnatal period. Therefore, the stage of maturation of individual components of the BBB and other brain barriers may play a central role in age-specific responses of an immature brain to cerebral ischemia and hypoxia, affecting injury subtypes, severity, and evolution. We discuss some of the most recent findings regarding the neurovascular responses of the immature brain to focal arterial stroke and modulation of these processes by inflammatory signaling." @default.
- W4250251081 created "2022-05-12" @default.
- W4250251081 creator A5025202949 @default.
- W4250251081 date "2016-01-01" @default.
- W4250251081 modified "2023-09-23" @default.
- W4250251081 title "Barrier Mechanisms in Neonatal Stroke" @default.
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- W4250251081 doi "https://doi.org/10.1007/978-3-319-32337-4_4" @default.
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