Matches in SemOpenAlex for { <https://semopenalex.org/work/W4250841111> ?p ?o ?g. }
- W4250841111 endingPage "2258" @default.
- W4250841111 startingPage "2250" @default.
- W4250841111 abstract "We examined the transcription of the hepatitis B virus surface antigen (HBsAg) gene in COS cells transfected with simian virus 40-based recombinant plasmids. When positioned behind the simian virus 40 late promoter, three transcripts were identified which hybridized to the HBsAg gene: a 2,000-nucleotide transcript colinear with a gene, a 1,100-nucleotide transcript representing a spliced molecule in which a major portion of the sequences encoding HBsAg were deleted, and an 800-nucleotide transcript derived primarily from sequences 3' to the HBsAg gene. The splice acceptor site utilized by the 1,100-nucleotide transcript is located immediately upstream of an open reading frame of unknown function contained within the 3' nontranslated region of the HBsAg gene. The HBsAg-specific mRNA species terminate 12 to 19 base pairs 3' of the sequence UAUAAA, similar to the concensus hexanucleotide which is thought to promote polyadenylation (AAUAAA). We constructed a series of plasmids with progressive deletions from the region surrounding where these transcripts terminate. Analysis of mRNA produced by cells transfected with these plasmids indicated that the signal hexanucleotide is in itself unable to promote the efficient processing of mRNA in the absence of downstream hepatitis B virus sequences. Processing proceeds properly, however, from plasmids containing an additional 30 nucleotides 3' of this signal." @default.
- W4250841111 created "2022-05-12" @default.
- W4250841111 creator A5004961206 @default.
- W4250841111 creator A5069806229 @default.
- W4250841111 date "1983-12-01" @default.
- W4250841111 modified "2023-10-16" @default.
- W4250841111 title "Analysis of Processing and Polyadenylation Signals of the Hepatitis B Virus Surface Antigen Gene by Using Simian Virus 40-Hepatitis B Virus Chimeric Plasmids" @default.
- W4250841111 cites W130566666 @default.
- W4250841111 cites W1440276721 @default.
- W4250841111 cites W1500727155 @default.
- W4250841111 cites W1512553642 @default.
- W4250841111 cites W1947261073 @default.
- W4250841111 cites W1963969100 @default.
- W4250841111 cites W1964021247 @default.
- W4250841111 cites W1964685458 @default.
- W4250841111 cites W1965051773 @default.
- W4250841111 cites W1965750507 @default.
- W4250841111 cites W1969600436 @default.
- W4250841111 cites W1971478237 @default.
- W4250841111 cites W1981445345 @default.
- W4250841111 cites W1984513339 @default.
- W4250841111 cites W1992595091 @default.
- W4250841111 cites W2000574331 @default.
- W4250841111 cites W2001923549 @default.
- W4250841111 cites W2014889375 @default.
- W4250841111 cites W2019179371 @default.
- W4250841111 cites W2020089973 @default.
- W4250841111 cites W2025653108 @default.
- W4250841111 cites W2028563796 @default.
- W4250841111 cites W2034247538 @default.
- W4250841111 cites W2040276985 @default.
- W4250841111 cites W2043108339 @default.
- W4250841111 cites W2043335783 @default.
- W4250841111 cites W2044648543 @default.
- W4250841111 cites W2045388587 @default.
- W4250841111 cites W2059421548 @default.
- W4250841111 cites W2063450941 @default.
- W4250841111 cites W2063719086 @default.
- W4250841111 cites W2065840327 @default.
- W4250841111 cites W2069630717 @default.
- W4250841111 cites W2075816835 @default.
- W4250841111 cites W2077077811 @default.
- W4250841111 cites W2077904565 @default.
- W4250841111 cites W2080187599 @default.
- W4250841111 cites W2082487884 @default.
- W4250841111 cites W2084678798 @default.
- W4250841111 cites W2088167128 @default.
- W4250841111 cites W2095413803 @default.
- W4250841111 cites W2109030204 @default.
- W4250841111 cites W2113597524 @default.
- W4250841111 cites W2129931102 @default.
- W4250841111 cites W2137583334 @default.
- W4250841111 cites W2138270253 @default.
- W4250841111 cites W2147722148 @default.
- W4250841111 cites W2171039952 @default.
- W4250841111 cites W284077946 @default.
- W4250841111 cites W3144051925 @default.
- W4250841111 cites W4238323916 @default.
- W4250841111 cites W4243215473 @default.
- W4250841111 cites W4253303333 @default.
- W4250841111 doi "https://doi.org/10.1128/mcb.3.12.2250-2258.1983" @default.
- W4250841111 hasPublicationYear "1983" @default.
- W4250841111 type Work @default.
- W4250841111 citedByCount "2" @default.
- W4250841111 crossrefType "journal-article" @default.
- W4250841111 hasAuthorship W4250841111A5004961206 @default.
- W4250841111 hasAuthorship W4250841111A5069806229 @default.
- W4250841111 hasConcept C104317684 @default.
- W4250841111 hasConcept C142575336 @default.
- W4250841111 hasConcept C153911025 @default.
- W4250841111 hasConcept C159047783 @default.
- W4250841111 hasConcept C22744801 @default.
- W4250841111 hasConcept C2522874641 @default.
- W4250841111 hasConcept C2777410769 @default.
- W4250841111 hasConcept C2780593183 @default.
- W4250841111 hasConcept C54355233 @default.
- W4250841111 hasConcept C67705224 @default.
- W4250841111 hasConcept C84148353 @default.
- W4250841111 hasConcept C86803240 @default.
- W4250841111 hasConceptScore W4250841111C104317684 @default.
- W4250841111 hasConceptScore W4250841111C142575336 @default.
- W4250841111 hasConceptScore W4250841111C153911025 @default.
- W4250841111 hasConceptScore W4250841111C159047783 @default.
- W4250841111 hasConceptScore W4250841111C22744801 @default.
- W4250841111 hasConceptScore W4250841111C2522874641 @default.
- W4250841111 hasConceptScore W4250841111C2777410769 @default.
- W4250841111 hasConceptScore W4250841111C2780593183 @default.
- W4250841111 hasConceptScore W4250841111C54355233 @default.
- W4250841111 hasConceptScore W4250841111C67705224 @default.
- W4250841111 hasConceptScore W4250841111C84148353 @default.
- W4250841111 hasConceptScore W4250841111C86803240 @default.
- W4250841111 hasIssue "12" @default.
- W4250841111 hasLocation W42508411111 @default.
- W4250841111 hasOpenAccess W4250841111 @default.
- W4250841111 hasPrimaryLocation W42508411111 @default.
- W4250841111 hasRelatedWork W1571771606 @default.
- W4250841111 hasRelatedWork W1979784258 @default.
- W4250841111 hasRelatedWork W2006079246 @default.