FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4250872732> ?p ?o ?g. }

• W4250872732 endingPage "4369" @default.
• W4250872732 startingPage "4366" @default.
• W4250872732 abstract "Abstract To define the basis for faulty granulopoiesis in patients with severe congenital neutropenia (SCN), the expression of granulocyte colony-stimulating factor receptor (G-CSFR) in primitive myeloid progenitor cells and their responsiveness to hematopoietic factors were studied. Flow cytometric analysis of bone marrow cells based on the expression of CD34, Kit receptor, and G-CSFR demonstrated a reduced frequency of CD34+/Kit+/ G-CSFR+cells in patients with SCN. The granulocyte-macrophage colony formation of CD34+/Kit+/G-CSFR+ cells in patients was markedly decreased in response to G-CSF alone and to the combination of stem cell factor, the ligand for flk2/flt3, and IL-3 with or without G-CSF in serum-deprived semisolid culture. In contrast, no difference in the responsiveness of CD34+/Kit+/G-CSFR− cells was noted between patients with SCN and subjects without SCN. These results demonstrate that the presence of qualitative and quantitative abnormalities of primitive myeloid progenitor cells expressing G-CSFR may play an important role in the impairment of granulopoiesis in patients with SCN." @default.
• W4250872732 created "2022-05-12" @default.
• W4250872732 creator A5002593805 @default.
• W4250872732 creator A5026891445 @default.
• W4250872732 creator A5027300481 @default.
• W4250872732 creator A5031775095 @default.
• W4250872732 creator A5034647954 @default.
• W4250872732 creator A5043895289 @default.
• W4250872732 creator A5046860113 @default.
• W4250872732 creator A5084617317 @default.
• W4250872732 creator A5086694128 @default.
• W4250872732 creator A5087043058 @default.
• W4250872732 creator A5088882696 @default.
• W4250872732 date "2000-12-15" @default.
• W4250872732 modified "2023-10-16" @default.
• W4250872732 title "Abnormalities of primitive myeloid progenitor cells expressing granulocyte colony-stimulating factor receptor in patients with severe congenital neutropenia" @default.
• W4250872732 cites W1509136795 @default.
• W4250872732 cites W1836124358 @default.
• W4250872732 cites W2009664834 @default.
• W4250872732 cites W2016011359 @default.
• W4250872732 cites W2017971949 @default.
• W4250872732 cites W202042235 @default.
• W4250872732 cites W2040937550 @default.
• W4250872732 cites W2079705202 @default.
• W4250872732 cites W2080518137 @default.
• W4250872732 cites W2114414627 @default.
• W4250872732 cites W2230805256 @default.
• W4250872732 cites W2262805112 @default.
• W4250872732 cites W2270245312 @default.
• W4250872732 cites W2280729002 @default.
• W4250872732 cites W2281552814 @default.
• W4250872732 cites W2410465152 @default.
• W4250872732 cites W2419202284 @default.
• W4250872732 cites W2460739979 @default.
• W4250872732 cites W310617275 @default.
• W4250872732 cites W344620921 @default.
• W4250872732 cites W346089124 @default.
• W4250872732 cites W4252438878 @default.
• W4250872732 doi "https://doi.org/10.1182/blood.v96.13.4366" @default.
• W4250872732 hasPublicationYear "2000" @default.
• W4250872732 type Work @default.
• W4250872732 citedByCount "10" @default.
• W4250872732 countsByYear W42508727322013 @default.
• W4250872732 crossrefType "journal-article" @default.
• W4250872732 hasAuthorship W4250872732A5002593805 @default.
• W4250872732 hasAuthorship W4250872732A5026891445 @default.
• W4250872732 hasAuthorship W4250872732A5027300481 @default.
• W4250872732 hasAuthorship W4250872732A5031775095 @default.
• W4250872732 hasAuthorship W4250872732A5034647954 @default.
• W4250872732 hasAuthorship W4250872732A5043895289 @default.
• W4250872732 hasAuthorship W4250872732A5046860113 @default.
• W4250872732 hasAuthorship W4250872732A5084617317 @default.
• W4250872732 hasAuthorship W4250872732A5086694128 @default.
• W4250872732 hasAuthorship W4250872732A5087043058 @default.
• W4250872732 hasAuthorship W4250872732A5088882696 @default.
• W4250872732 hasConcept C10205521 @default.
• W4250872732 hasConcept C109159458 @default.
• W4250872732 hasConcept C126322002 @default.
• W4250872732 hasConcept C131665280 @default.
• W4250872732 hasConcept C14942488 @default.
• W4250872732 hasConcept C201750760 @default.
• W4250872732 hasConcept C2022786 @default.
• W4250872732 hasConcept C203014093 @default.
• W4250872732 hasConcept C2776090121 @default.
• W4250872732 hasConcept C2776694085 @default.
• W4250872732 hasConcept C2777063308 @default.
• W4250872732 hasConcept C2777767877 @default.
• W4250872732 hasConcept C2777983669 @default.
• W4250872732 hasConcept C2779282312 @default.
• W4250872732 hasConcept C2779452902 @default.
• W4250872732 hasConcept C2780007613 @default.
• W4250872732 hasConcept C28328180 @default.
• W4250872732 hasConcept C502942594 @default.
• W4250872732 hasConcept C67662055 @default.
• W4250872732 hasConcept C71924100 @default.
• W4250872732 hasConcept C86803240 @default.
• W4250872732 hasConcept C8891405 @default.
• W4250872732 hasConcept C95444343 @default.
• W4250872732 hasConcept C95862172 @default.
• W4250872732 hasConceptScore W4250872732C10205521 @default.
• W4250872732 hasConceptScore W4250872732C109159458 @default.
• W4250872732 hasConceptScore W4250872732C126322002 @default.
• W4250872732 hasConceptScore W4250872732C131665280 @default.
• W4250872732 hasConceptScore W4250872732C14942488 @default.
• W4250872732 hasConceptScore W4250872732C201750760 @default.
• W4250872732 hasConceptScore W4250872732C2022786 @default.
• W4250872732 hasConceptScore W4250872732C203014093 @default.
• W4250872732 hasConceptScore W4250872732C2776090121 @default.
• W4250872732 hasConceptScore W4250872732C2776694085 @default.
• W4250872732 hasConceptScore W4250872732C2777063308 @default.
• W4250872732 hasConceptScore W4250872732C2777767877 @default.
• W4250872732 hasConceptScore W4250872732C2777983669 @default.
• W4250872732 hasConceptScore W4250872732C2779282312 @default.
• W4250872732 hasConceptScore W4250872732C2779452902 @default.
• W4250872732 hasConceptScore W4250872732C2780007613 @default.
• W4250872732 hasConceptScore W4250872732C28328180 @default.
• W4250872732 hasConceptScore W4250872732C502942594 @default.
• W4250872732 hasConceptScore W4250872732C67662055 @default.

• next