Matches in SemOpenAlex for { <https://semopenalex.org/work/W4251014195> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W4251014195 endingPage "293" @default.
- W4251014195 startingPage "293" @default.
- W4251014195 abstract "An 18-residue peptide, corresponding to the minimum sequence of the N-terminal zinc-finger domain in the nucleocapsid of human T-lymphotrophic virus type I, was synthesized by a solid-phase method and fully characterized. Its ability to complex metal ions (Co2+ and Zn2+) was clearly established by UV–visible spectroscopy and MS. The stability of these complexes was investigated by an original method with HPLC chromatography. Our results show that, even in the presence of air, the Zn2+ complex is highly stable. In contrast, the Co2+ complex undergoes a relatively fast degradation due to an intramolecular oxidation leading to the formation of a disulphide bridge between two cysteine residues. The 1H-NMR analysis indicates that Zn2+ binds to the Nδ atom of the histidine residue rather than to the Nε atom. Two-dimensional NMR techniques were used to determine the solution structure of the zinc-finger, illustrated by the existence of turns in the overall conformation." @default.
- W4251014195 created "2022-05-12" @default.
- W4251014195 creator A5019942340 @default.
- W4251014195 creator A5054157424 @default.
- W4251014195 creator A5059043236 @default.
- W4251014195 creator A5061103693 @default.
- W4251014195 creator A5088395441 @default.
- W4251014195 date "2000-12-01" @default.
- W4251014195 modified "2023-10-05" @default.
- W4251014195 title "Human T-lymphotrophic virus type I nucleocapsid protein NCp15: structural study and stability of the N-terminal zinc-finger" @default.
- W4251014195 doi "https://doi.org/10.1042/0264-6021:3520293" @default.
- W4251014195 hasPublicationYear "2000" @default.
- W4251014195 type Work @default.
- W4251014195 citedByCount "0" @default.
- W4251014195 crossrefType "journal-article" @default.
- W4251014195 hasAuthorship W4251014195A5019942340 @default.
- W4251014195 hasAuthorship W4251014195A5054157424 @default.
- W4251014195 hasAuthorship W4251014195A5059043236 @default.
- W4251014195 hasAuthorship W4251014195A5061103693 @default.
- W4251014195 hasAuthorship W4251014195A5088395441 @default.
- W4251014195 hasBestOaLocation W42510141952 @default.
- W4251014195 hasConcept C104317684 @default.
- W4251014195 hasConcept C178790620 @default.
- W4251014195 hasConcept C181199279 @default.
- W4251014195 hasConcept C185592680 @default.
- W4251014195 hasConcept C24284526 @default.
- W4251014195 hasConcept C2778460671 @default.
- W4251014195 hasConcept C2779201268 @default.
- W4251014195 hasConcept C2779281246 @default.
- W4251014195 hasConcept C2781338088 @default.
- W4251014195 hasConcept C515207424 @default.
- W4251014195 hasConcept C535196362 @default.
- W4251014195 hasConcept C55493867 @default.
- W4251014195 hasConcept C66974803 @default.
- W4251014195 hasConcept C71240020 @default.
- W4251014195 hasConcept C75079739 @default.
- W4251014195 hasConcept C8010536 @default.
- W4251014195 hasConcept C86339819 @default.
- W4251014195 hasConceptScore W4251014195C104317684 @default.
- W4251014195 hasConceptScore W4251014195C178790620 @default.
- W4251014195 hasConceptScore W4251014195C181199279 @default.
- W4251014195 hasConceptScore W4251014195C185592680 @default.
- W4251014195 hasConceptScore W4251014195C24284526 @default.
- W4251014195 hasConceptScore W4251014195C2778460671 @default.
- W4251014195 hasConceptScore W4251014195C2779201268 @default.
- W4251014195 hasConceptScore W4251014195C2779281246 @default.
- W4251014195 hasConceptScore W4251014195C2781338088 @default.
- W4251014195 hasConceptScore W4251014195C515207424 @default.
- W4251014195 hasConceptScore W4251014195C535196362 @default.
- W4251014195 hasConceptScore W4251014195C55493867 @default.
- W4251014195 hasConceptScore W4251014195C66974803 @default.
- W4251014195 hasConceptScore W4251014195C71240020 @default.
- W4251014195 hasConceptScore W4251014195C75079739 @default.
- W4251014195 hasConceptScore W4251014195C8010536 @default.
- W4251014195 hasConceptScore W4251014195C86339819 @default.
- W4251014195 hasIssue "2" @default.
- W4251014195 hasLocation W42510141951 @default.
- W4251014195 hasLocation W42510141952 @default.
- W4251014195 hasOpenAccess W4251014195 @default.
- W4251014195 hasPrimaryLocation W42510141951 @default.
- W4251014195 hasRelatedWork W1260787347 @default.
- W4251014195 hasRelatedWork W1969212998 @default.
- W4251014195 hasRelatedWork W1983233853 @default.
- W4251014195 hasRelatedWork W2012807229 @default.
- W4251014195 hasRelatedWork W2028212238 @default.
- W4251014195 hasRelatedWork W2130473428 @default.
- W4251014195 hasRelatedWork W2146747437 @default.
- W4251014195 hasRelatedWork W2208190997 @default.
- W4251014195 hasRelatedWork W2531836857 @default.
- W4251014195 hasRelatedWork W2603391523 @default.
- W4251014195 hasVolume "352" @default.
- W4251014195 isParatext "false" @default.
- W4251014195 isRetracted "false" @default.
- W4251014195 workType "article" @default.