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- W4251170040 abstract "The effect of acetylsalicylic acid (ASA) on capsaicin-evoked activation of cutaneous nociceptors was tested in a double blind study in 10 volunteers. Capsaicin (2% in ethanol) was applied topically for 30 min. Topical ASA (0.25 g/ml) reduced pain intensity and axon reflex flare size. Also, areas of secondary hyperalgesia to light touch and pin-prick were diminished. In contrast, capsaicin-induced heat hyperalgesia was unaffected by ASA. It is concluded that ASA counteracts the excitatory effects of capsaicin on nociceptors and mechanical hyperalgesia but not its sensitizing action to heat." @default.
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- W4251170040 date "1996-08-16" @default.
- W4251170040 modified "2023-10-18" @default.
- W4251170040 title "Topical acetylsalicylate attenuates capsaicin induced pain, flare and allodynia but not thermal hyperalgesia" @default.
- W4251170040 doi "https://doi.org/10.1016/s0304-3940(96)12868-8" @default.
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