FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4251188891> ?p ?o ?g. }

• W4251188891 endingPage "1119" @default.
• W4251188891 startingPage "1114" @default.
• W4251188891 abstract "ALTHOUGH THE ASSOCIATION between optic glioma and neurofibromatosis is well recognized, few studies have systematically compared the outcomes of patients with optic gliomas and neurofibromatosis and patients with optic gliomas without neurofibromatosis. In the present study, patients with optic gliomas and Type 1 neurofibromatosis (NF-1) were compared with patients with optic gliomas without NF-1, with respect to survival, time to tumor progression, and tumor location. Forty-four patients with optic gliomas who were evaluated between 1949 and 1991 were studied retrospectively. Sixteen of 44 patients(36%) met the National Institutes of Health criteria for NF-1. The medical records of all patients were examined, and letters of inquiry were sent to every living patient to ascertain current health statuses. Death certificates were obtained to determine causes of death. Follow-up averaged 7.2 years (10.2 yr for patients with NF-1, 5.4 yr for patients without NF-1). The 5- and 10-year survival rates for patients with optic gliomas and NF-1 were 93 and 81%, respectively. For those patients with optic gliomas who did not have NF-1, 5- and 10-year survival rates were 83 and 76%, respectively. Seventeen patients experienced tumor progression (5 with NF-1, 12 without NF-1). A difference was observed in the mean time to tumor progression (first relapse) between the two groups (mean time with NF-1, 8.37 yr; without NF-1, 2.39 yr[P < 0.01]). However, no significant difference in overall survival, as evaluated by a log-rank test of the respective Kaplan-Meier survival curves, was observed between the two groups. A significant difference in distribution of tumor location between the group with NF-1 and the group without NF-1 was also noted (Fisher's exact test, P = 0.0338), although the number of patients evaluated in this series was too small to determine whether this difference in tumor location influenced relapse rate. We conclude that optic gliomas in patients with neurofibromatosis have a different distribution of location as opposed to those in patients without neurofibromatosis, and, for first relapse, the presence of neurofibromatosis is a significant favorable factor." @default.
• W4251188891 created "2022-05-12" @default.
• W4251188891 creator A5006262715 @default.
• W4251188891 creator A5018603514 @default.
• W4251188891 creator A5052723086 @default.
• W4251188891 date "1996-06-01" @default.
• W4251188891 modified "2023-10-15" @default.
• W4251188891 title "Prognostic Significance of Type 1 Neurofibromatosis (von Recklinghausen Disease) in Childhood Optic Glioma" @default.
• W4251188891 cites W177661409 @default.
• W4251188891 cites W1979529318 @default.
• W4251188891 cites W1987987887 @default.
• W4251188891 cites W1991298960 @default.
• W4251188891 cites W1991933360 @default.
• W4251188891 cites W2036647391 @default.
• W4251188891 cites W2037920362 @default.
• W4251188891 cites W2073786389 @default.
• W4251188891 cites W2076794162 @default.
• W4251188891 cites W2081228385 @default.
• W4251188891 cites W2085111388 @default.
• W4251188891 cites W2085792148 @default.
• W4251188891 cites W2102858476 @default.
• W4251188891 cites W2117072026 @default.
• W4251188891 cites W2126527708 @default.
• W4251188891 cites W2139478740 @default.
• W4251188891 cites W2330798445 @default.
• W4251188891 doi "https://doi.org/10.1227/00006123-199606000-00010" @default.
• W4251188891 hasPublicationYear "1996" @default.
• W4251188891 type Work @default.
• W4251188891 citedByCount "2" @default.
• W4251188891 countsByYear W42511888912016 @default.
• W4251188891 crossrefType "journal-article" @default.
• W4251188891 hasAuthorship W4251188891A5006262715 @default.
• W4251188891 hasAuthorship W4251188891A5018603514 @default.
• W4251188891 hasAuthorship W4251188891A5052723086 @default.
• W4251188891 hasConcept C118487528 @default.
• W4251188891 hasConcept C121608353 @default.
• W4251188891 hasConcept C126322002 @default.
• W4251188891 hasConcept C141071460 @default.
• W4251188891 hasConcept C142724271 @default.
• W4251188891 hasConcept C2778227246 @default.
• W4251188891 hasConcept C2778984943 @default.
• W4251188891 hasConcept C2779134260 @default.
• W4251188891 hasConcept C2779256057 @default.
• W4251188891 hasConcept C2780837183 @default.
• W4251188891 hasConcept C502942594 @default.
• W4251188891 hasConcept C71924100 @default.
• W4251188891 hasConcept C90924648 @default.
• W4251188891 hasConceptScore W4251188891C118487528 @default.
• W4251188891 hasConceptScore W4251188891C121608353 @default.
• W4251188891 hasConceptScore W4251188891C126322002 @default.
• W4251188891 hasConceptScore W4251188891C141071460 @default.
• W4251188891 hasConceptScore W4251188891C142724271 @default.
• W4251188891 hasConceptScore W4251188891C2778227246 @default.
• W4251188891 hasConceptScore W4251188891C2778984943 @default.
• W4251188891 hasConceptScore W4251188891C2779134260 @default.
• W4251188891 hasConceptScore W4251188891C2779256057 @default.
• W4251188891 hasConceptScore W4251188891C2780837183 @default.
• W4251188891 hasConceptScore W4251188891C502942594 @default.
• W4251188891 hasConceptScore W4251188891C71924100 @default.
• W4251188891 hasConceptScore W4251188891C90924648 @default.
• W4251188891 hasIssue "6" @default.
• W4251188891 hasLocation W42511888911 @default.
• W4251188891 hasOpenAccess W4251188891 @default.
• W4251188891 hasPrimaryLocation W42511888911 @default.
• W4251188891 hasRelatedWork W1984608671 @default.
• W4251188891 hasRelatedWork W2003322706 @default.
• W4251188891 hasRelatedWork W2234322404 @default.
• W4251188891 hasRelatedWork W2389017212 @default.
• W4251188891 hasRelatedWork W2411243649 @default.
• W4251188891 hasRelatedWork W2412849376 @default.
• W4251188891 hasRelatedWork W2897072461 @default.
• W4251188891 hasRelatedWork W2944910448 @default.
• W4251188891 hasRelatedWork W3032348021 @default.
• W4251188891 hasRelatedWork W2081495422 @default.
• W4251188891 hasVolume "38" @default.
• W4251188891 isParatext "false" @default.
• W4251188891 isRetracted "false" @default.
• W4251188891 workType "article" @default.