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- W4251411936 abstract "We studied the mechanism of antagonism of p-chloroamphetamine-induced neurotoxicity by dextromethorphan. The pretreatment with potent and selective σ receptor ligands, 4-phenyl-4-(1-phenylbutyl)piperidine (4-PPBP) and N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]-ethylamine monohydrochloride (NE-100), did not alter the reduction of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in the cerebral cortex by repeated administration of p-chloroamphetamine. These results suggest that σ receptors might not play a significant role in the antagonism of p-chloroamphetamine-induced neurotoxicity by dextromethorphan." @default.
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- W4251411936 date "1995-10-06" @default.
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- W4251411936 title "Lack of neuroprotective effect of σ receptor ligands in the neurotoxicity of -chloroamphetamine in rat brain" @default.
- W4251411936 doi "https://doi.org/10.1016/s0922-4106(05)80055-0" @default.
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