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• W4251414021 abstract "Liposomal nanoparticles (LNs) encapsulating therapeutic agents, or liposomal nanomedicines, represent an advanced class of drug delivery systems, with several formulations presently on the market and many more in clinical trials. Over the past 20 years, a variety of techniques have been developed for encapsulating both conventional drugs (such as anticancer drugs and antibiotics) and the new genetic drugs (plasmid DNA containing therapeutic genes, antisense oligonucleotides and small interfering RNA) within LNs. If the LNs possess certain properties, they tend to accumulate at sites of disease, such as tumours, where the endothelial layer is ‘leaky’ and allows extravasation of particles with small diameters. These properties include a diameter centred on 100 nm, a high drug-to-lipid ratio, excellent retention of the encapsulated drug, and a long (> 6 h) circulation lifetime. These properties permit the LNs to protect their contents during circulation, prevent contact with healthy tissues, and accumulate at sites of disease. The authors discuss recent advances in this field involving conventional anticancer drugs, as well as applications involving gene delivery, stimulation of the immune system and silencing of unwanted gene expression. Liposomal nanomedicines have the potential to offer new treatments in such areas as cancer therapy, vaccine development and cholesterol management." @default.
• W4251414021 created "2022-05-12" @default.
• W4251414021 creator A5050350074 @default.
• W4251414021 creator A5088028621 @default.
• W4251414021 date "2007-12-21" @default.
• W4251414021 modified "2023-10-11" @default.
• W4251414021 title "Liposomal nanomedicines" @default.
• W4251414021 cites W1498020422 @default.
• W4251414021 cites W1514540900 @default.
• W4251414021 cites W1522777551 @default.
• W4251414021 cites W1535876276 @default.
• W4251414021 cites W1578857830 @default.
• W4251414021 cites W163963336 @default.
• W4251414021 cites W1966334833 @default.
• W4251414021 cites W1969072247 @default.
• W4251414021 cites W1969402650 @default.
• W4251414021 cites W1970206786 @default.
• W4251414021 cites W1971373442 @default.
• W4251414021 cites W1973579525 @default.
• W4251414021 cites W1973884421 @default.
• W4251414021 cites W1984090232 @default.
• W4251414021 cites W1986117384 @default.
• W4251414021 cites W1986516374 @default.
• W4251414021 cites W1991930393 @default.
• W4251414021 cites W1992497818 @default.
• W4251414021 cites W1996517371 @default.
• W4251414021 cites W1997772128 @default.
• W4251414021 cites W2002516695 @default.
• W4251414021 cites W2003178300 @default.
• W4251414021 cites W2003552025 @default.
• W4251414021 cites W2009570513 @default.
• W4251414021 cites W2011938535 @default.
• W4251414021 cites W2012519514 @default.
• W4251414021 cites W2013342651 @default.
• W4251414021 cites W2013470095 @default.
• W4251414021 cites W2020368715 @default.
• W4251414021 cites W2025345914 @default.
• W4251414021 cites W2025919388 @default.
• W4251414021 cites W2028065774 @default.
• W4251414021 cites W2029827106 @default.
• W4251414021 cites W2033042607 @default.
• W4251414021 cites W2036839119 @default.
• W4251414021 cites W2036944284 @default.
• W4251414021 cites W2037048276 @default.
• W4251414021 cites W2037501805 @default.
• W4251414021 cites W2037563014 @default.
• W4251414021 cites W2040876516 @default.
• W4251414021 cites W2044945512 @default.
• W4251414021 cites W2049043423 @default.
• W4251414021 cites W2049398377 @default.
• W4251414021 cites W2053177686 @default.
• W4251414021 cites W2055265722 @default.
• W4251414021 cites W2055402663 @default.
• W4251414021 cites W2058015212 @default.
• W4251414021 cites W2062162771 @default.
• W4251414021 cites W2063119239 @default.
• W4251414021 cites W2065135000 @default.
• W4251414021 cites W2065359597 @default.
• W4251414021 cites W2066861571 @default.
• W4251414021 cites W2068524399 @default.
• W4251414021 cites W2069331972 @default.
• W4251414021 cites W2069981713 @default.
• W4251414021 cites W2073773999 @default.
• W4251414021 cites W2075078368 @default.
• W4251414021 cites W2075427224 @default.
• W4251414021 cites W2076124962 @default.
• W4251414021 cites W2076361525 @default.
• W4251414021 cites W2078775246 @default.
• W4251414021 cites W2079189432 @default.
• W4251414021 cites W2083014834 @default.
• W4251414021 cites W2086919915 @default.
• W4251414021 cites W2087146189 @default.
• W4251414021 cites W2088694674 @default.
• W4251414021 cites W2092836675 @default.
• W4251414021 cites W2093007266 @default.
• W4251414021 cites W2093469424 @default.
• W4251414021 cites W2095151181 @default.
• W4251414021 cites W2095399328 @default.
• W4251414021 cites W2097611004 @default.
• W4251414021 cites W2102966245 @default.
• W4251414021 cites W2103207585 @default.
• W4251414021 cites W2105364677 @default.
• W4251414021 cites W2106095037 @default.
• W4251414021 cites W2106147991 @default.
• W4251414021 cites W2107327713 @default.
• W4251414021 cites W2107638822 @default.
• W4251414021 cites W2114959684 @default.
• W4251414021 cites W2117761826 @default.
• W4251414021 cites W2119110692 @default.
• W4251414021 cites W2119293746 @default.
• W4251414021 cites W2119464903 @default.
• W4251414021 cites W2120694339 @default.
• W4251414021 cites W2122044626 @default.
• W4251414021 cites W2122917250 @default.
• W4251414021 cites W2128398215 @default.
• W4251414021 cites W2129309504 @default.
• W4251414021 cites W2129550547 @default.
• W4251414021 cites W2133782648 @default.

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