FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4251566501> ?p ?o ?g. }

• W4251566501 endingPage "1895" @default.
• W4251566501 startingPage "1887" @default.
• W4251566501 abstract "Abstract The Japanese medaka fish Oryzias latipes has an XX/XY sex-determination system. The Y-linked sex-determination gene DMY is a duplicate of the autosomal gene DMRT1, which encodes a DM-domain-containing transcriptional factor. DMY appears to have originated recently within Oryzias, allowing a detailed evolutionary study of the initial steps that led to the new gene and new sex-determination system. Here I analyze the publicly available DMRT1 and DMY gene sequences of Oryzias species and report the following findings. First, the synonymous substitution rate in DMY is 1.73 times that in DMRT1, consistent with the male-driven evolution hypothesis. Second, the ratio of the rate of nonsynonymous nucleotide substitution (dN) to that of synonymous substitution (dS) is significantly higher in DMY than in DMRT1. Third, in DMRT1, the dN/dS ratio for the DM domain is lower than that for non-DM regions, as expected from the functional importance of the DM domain. But in DMY, the opposite is observed and the DM domain is likely under positive Darwinian selection. Fourth, only one characteristic amino acid distinguishes all DMY sequences from all DMRT1 sequences, suggesting that a single amino acid change may be largely responsible for the establishment of DMY as the male sex-determination gene in medaka fish." @default.
• W4251566501 created "2022-05-12" @default.
• W4251566501 creator A5082143549 @default.
• W4251566501 date "2004-04-01" @default.
• W4251566501 modified "2023-10-16" @default.
• W4251566501 title "Evolution of <i>DMY</i>, a Newly Emergent Male Sex-Determination Gene of Medaka Fish" @default.
• W4251566501 cites W1495499445 @default.
• W4251566501 cites W1562825769 @default.
• W4251566501 cites W1594381616 @default.
• W4251566501 cites W1964945206 @default.
• W4251566501 cites W1971231926 @default.
• W4251566501 cites W1982589225 @default.
• W4251566501 cites W1984104678 @default.
• W4251566501 cites W1984470203 @default.
• W4251566501 cites W1984501537 @default.
• W4251566501 cites W1989882854 @default.
• W4251566501 cites W1990335021 @default.
• W4251566501 cites W1991873334 @default.
• W4251566501 cites W1998646180 @default.
• W4251566501 cites W1999304649 @default.
• W4251566501 cites W2004370095 @default.
• W4251566501 cites W2010886990 @default.
• W4251566501 cites W2013246689 @default.
• W4251566501 cites W2013355786 @default.
• W4251566501 cites W2017205393 @default.
• W4251566501 cites W2022981694 @default.
• W4251566501 cites W2027318023 @default.
• W4251566501 cites W2030966943 @default.
• W4251566501 cites W2031670682 @default.
• W4251566501 cites W2032760076 @default.
• W4251566501 cites W2037313882 @default.
• W4251566501 cites W2048028231 @default.
• W4251566501 cites W2050669549 @default.
• W4251566501 cites W2055330038 @default.
• W4251566501 cites W2058795503 @default.
• W4251566501 cites W2061092924 @default.
• W4251566501 cites W2065461553 @default.
• W4251566501 cites W2085494643 @default.
• W4251566501 cites W2086057335 @default.
• W4251566501 cites W2090223604 @default.
• W4251566501 cites W2094434685 @default.
• W4251566501 cites W2097382368 @default.
• W4251566501 cites W2098452577 @default.
• W4251566501 cites W2100856331 @default.
• W4251566501 cites W2102190537 @default.
• W4251566501 cites W2102424972 @default.
• W4251566501 cites W2112146544 @default.
• W4251566501 cites W2114336300 @default.
• W4251566501 cites W2116111392 @default.
• W4251566501 cites W2125342554 @default.
• W4251566501 cites W2136344019 @default.
• W4251566501 cites W2137638457 @default.
• W4251566501 cites W2140656514 @default.
• W4251566501 cites W2149943693 @default.
• W4251566501 cites W2156434383 @default.
• W4251566501 cites W2157847015 @default.
• W4251566501 cites W2158216739 @default.
• W4251566501 cites W2160364329 @default.
• W4251566501 cites W2162273481 @default.
• W4251566501 cites W2171498188 @default.
• W4251566501 cites W4229487902 @default.
• W4251566501 cites W4293003414 @default.
• W4251566501 doi "https://doi.org/10.1093/genetics/166.4.1887" @default.
• W4251566501 hasPublicationYear "2004" @default.
• W4251566501 type Work @default.
• W4251566501 citedByCount "9" @default.
• W4251566501 countsByYear W42515665012020 @default.
• W4251566501 countsByYear W42515665012021 @default.
• W4251566501 crossrefType "journal-article" @default.
• W4251566501 hasAuthorship W4251566501A5082143549 @default.
• W4251566501 hasBestOaLocation W42515665011 @default.
• W4251566501 hasConcept C104317684 @default.
• W4251566501 hasConcept C138025448 @default.
• W4251566501 hasConcept C141231307 @default.
• W4251566501 hasConcept C149904235 @default.
• W4251566501 hasConcept C2777289358 @default.
• W4251566501 hasConcept C2780246931 @default.
• W4251566501 hasConcept C54355233 @default.
• W4251566501 hasConcept C73456138 @default.
• W4251566501 hasConcept C7386963 @default.
• W4251566501 hasConcept C78458016 @default.
• W4251566501 hasConcept C86803240 @default.
• W4251566501 hasConcept C87253356 @default.
• W4251566501 hasConceptScore W4251566501C104317684 @default.
• W4251566501 hasConceptScore W4251566501C138025448 @default.
• W4251566501 hasConceptScore W4251566501C141231307 @default.
• W4251566501 hasConceptScore W4251566501C149904235 @default.
• W4251566501 hasConceptScore W4251566501C2777289358 @default.
• W4251566501 hasConceptScore W4251566501C2780246931 @default.
• W4251566501 hasConceptScore W4251566501C54355233 @default.
• W4251566501 hasConceptScore W4251566501C73456138 @default.
• W4251566501 hasConceptScore W4251566501C7386963 @default.
• W4251566501 hasConceptScore W4251566501C78458016 @default.
• W4251566501 hasConceptScore W4251566501C86803240 @default.
• W4251566501 hasConceptScore W4251566501C87253356 @default.
• W4251566501 hasIssue "4" @default.
• W4251566501 hasLocation W42515665011 @default.
• W4251566501 hasOpenAccess W4251566501 @default.

• next