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- W4251569320 abstract "Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans and its incidence continues to rise. Although CSCC usually display a benign clinical behavior, it can be both locally invasive and metastatic. The signaling pathways involved in CSCC development have given rise to targetable molecules in recent decades. In addition, the high mutational burden and increased risk of CSCC in patients under immunosuppression were part of the rationale for developing the immunotherapy for CSCC that has changed the therapeutic landscape. Several drugs have been developed for CSCC treatment, but the disease may actually be induced by drugs as well. Molecular mechanisms underlie pharmacologically-induced CSCC, and a sound knowledge of them could help physicians better tackle this tumor. " @default.
- W4251569320 created "2022-05-12" @default.
- W4251569320 creator A5019875062 @default.
- W4251569320 date "2020-04-25" @default.
- W4251569320 modified "2023-10-16" @default.
- W4251569320 title "Pharmacologically Induced Cutaneous Squamous Cell Carcinoma" @default.
- W4251569320 doi "https://doi.org/10.32545/encyclopedia202004.0021.v1" @default.
- W4251569320 hasPublicationYear "2020" @default.
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