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- W4251738327 abstract "University of Toronto, Sunnybrook Health Science Centre, Toronto, Ontario, Canada. beverley.orser@utoronto.caIn Reply:— I thank Dr. Roy for his thoughtful integration of the three editorials.1–3His broad overview of the evolution of anesthetic practice highlights two important points. As a result of the hard work of our forefathers, we have developed a remarkable understanding of “what anesthetics do.” These insights have produced unprecedented advances in patient safety, primarily as a result of improved monitoring and drug delivery systems. However, we are also reminded that we still don't understand “how anesthetics work.” This lack of knowledge has resulted in a paucity of radically new anesthetic drugs which, in turn, has contributed to a plateau in anesthesia-related mortality.4The specialty of anesthesiology must be ambitious and relentless in its efforts to develop safer anesthetic drugs and improved drug administration strategies. This effort will require a firm commitment to train young investigators who will bring the best science to bear on this important goal.University of Toronto, Sunnybrook Health Science Centre, Toronto, Ontario, Canada. beverley.orser@utoronto.ca" @default.
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- W4251738327 date "2009-08-01" @default.
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- W4251738327 title "Three Editorials—Three Historical Allusions" @default.
- W4251738327 doi "https://doi.org/10.1097/aln.0b013e3181ac712d" @default.
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