FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4251752650> ?p ?o ?g. }

• W4251752650 endingPage "3565" @default.
• W4251752650 startingPage "3562" @default.
• W4251752650 abstract "The factor II G20210A mutation is a recently identified congenital risk factor for venous thrombosis. Its role in artery disease is still undefined. We investigated 72 patients (35 male and 37 female) with documented ischemic stroke occurred before 50 years of age and without risk factors such as diabetes, hypertension, and hyperlipidemia; 198 thrombosis-free individuals were investigated as the control group. We found 7 heterozygotes (9.7%) and 2 homozygotes (2.7%) for the mutant factor II allele among the patients and 5 heterozygotes (2.5%) among the controls; the mutant factor II allele frequency in the patient group (7.6%, 95% confidence interval [CI], 3.3 to 11.9) was significantly higher than in the controls (1.2%; 95% CI, 0.1 to 2.3;P = .0001). The prevalence of other investigated mutant alleles (factor V G1691A, methylenetetrahydrofolate reductase C677T) did not significantly differ between the two groups. The odds ratio for ischemic stroke associated with the carriership of the mutant factor II allele (both heterozygous and homozygous genotypes) was 5.1 (95% CI, 1.6 to 16.3). Heterozygous genotype was associated with a 3.8-fold increased risk for cerebral ischemia (95% CI, 1.1 to 13.1); in particular, assuming an expected prevalence of homozygotes in the general population of 1.6 to 10,000 according to the Hardy-Weinberg equilibrium, the risk associated with the homozygous genotype was estimated exceedingly high, being increased 208-fold." @default.
• W4251752650 created "2022-05-12" @default.
• W4251752650 creator A5016603192 @default.
• W4251752650 creator A5016641239 @default.
• W4251752650 creator A5021547579 @default.
• W4251752650 creator A5026279249 @default.
• W4251752650 creator A5042424261 @default.
• W4251752650 creator A5045480399 @default.
• W4251752650 creator A5052893667 @default.
• W4251752650 creator A5054304877 @default.
• W4251752650 creator A5056633560 @default.
• W4251752650 date "1998-05-15" @default.
• W4251752650 modified "2023-09-27" @default.
• W4251752650 title "Prothrombin G20210A Mutant Genotype Is a Risk Factor for Cerebrovascular Ischemic Disease in Young Patients" @default.
• W4251752650 cites W1485388354 @default.
• W4251752650 cites W1531281563 @default.
• W4251752650 cites W159656921 @default.
• W4251752650 cites W1965958910 @default.
• W4251752650 cites W1973704397 @default.
• W4251752650 cites W1992127247 @default.
• W4251752650 cites W2101371933 @default.
• W4251752650 cites W2165715420 @default.
• W4251752650 cites W2408270223 @default.
• W4251752650 cites W4242674909 @default.
• W4251752650 doi "https://doi.org/10.1182/blood.v91.10.3562.3562_3562_3565" @default.
• W4251752650 hasPublicationYear "1998" @default.
• W4251752650 type Work @default.
• W4251752650 citedByCount "6" @default.
• W4251752650 countsByYear W42517526502021 @default.
• W4251752650 countsByYear W42517526502022 @default.
• W4251752650 countsByYear W42517526502023 @default.
• W4251752650 crossrefType "journal-article" @default.
• W4251752650 hasAuthorship W4251752650A5016603192 @default.
• W4251752650 hasAuthorship W4251752650A5016641239 @default.
• W4251752650 hasAuthorship W4251752650A5021547579 @default.
• W4251752650 hasAuthorship W4251752650A5026279249 @default.
• W4251752650 hasAuthorship W4251752650A5042424261 @default.
• W4251752650 hasAuthorship W4251752650A5045480399 @default.
• W4251752650 hasAuthorship W4251752650A5052893667 @default.
• W4251752650 hasAuthorship W4251752650A5054304877 @default.
• W4251752650 hasAuthorship W4251752650A5056633560 @default.
• W4251752650 hasBestOaLocation W42517526501 @default.
• W4251752650 hasConcept C104317684 @default.
• W4251752650 hasConcept C126322002 @default.
• W4251752650 hasConcept C127413603 @default.
• W4251752650 hasConcept C134018914 @default.
• W4251752650 hasConcept C135763542 @default.
• W4251752650 hasConcept C153471976 @default.
• W4251752650 hasConcept C156957248 @default.
• W4251752650 hasConcept C180754005 @default.
• W4251752650 hasConcept C2776046644 @default.
• W4251752650 hasConcept C2777175894 @default.
• W4251752650 hasConcept C2780011451 @default.
• W4251752650 hasConcept C2780645631 @default.
• W4251752650 hasConcept C2780868729 @default.
• W4251752650 hasConcept C2908647359 @default.
• W4251752650 hasConcept C50440223 @default.
• W4251752650 hasConcept C54355233 @default.
• W4251752650 hasConcept C71924100 @default.
• W4251752650 hasConcept C78519656 @default.
• W4251752650 hasConcept C86803240 @default.
• W4251752650 hasConcept C90924648 @default.
• W4251752650 hasConcept C99454951 @default.
• W4251752650 hasConceptScore W4251752650C104317684 @default.
• W4251752650 hasConceptScore W4251752650C126322002 @default.
• W4251752650 hasConceptScore W4251752650C127413603 @default.
• W4251752650 hasConceptScore W4251752650C134018914 @default.
• W4251752650 hasConceptScore W4251752650C135763542 @default.
• W4251752650 hasConceptScore W4251752650C153471976 @default.
• W4251752650 hasConceptScore W4251752650C156957248 @default.
• W4251752650 hasConceptScore W4251752650C180754005 @default.
• W4251752650 hasConceptScore W4251752650C2776046644 @default.
• W4251752650 hasConceptScore W4251752650C2777175894 @default.
• W4251752650 hasConceptScore W4251752650C2780011451 @default.
• W4251752650 hasConceptScore W4251752650C2780645631 @default.
• W4251752650 hasConceptScore W4251752650C2780868729 @default.
• W4251752650 hasConceptScore W4251752650C2908647359 @default.
• W4251752650 hasConceptScore W4251752650C50440223 @default.
• W4251752650 hasConceptScore W4251752650C54355233 @default.
• W4251752650 hasConceptScore W4251752650C71924100 @default.
• W4251752650 hasConceptScore W4251752650C78519656 @default.
• W4251752650 hasConceptScore W4251752650C86803240 @default.
• W4251752650 hasConceptScore W4251752650C90924648 @default.
• W4251752650 hasConceptScore W4251752650C99454951 @default.
• W4251752650 hasIssue "10" @default.
• W4251752650 hasLocation W42517526501 @default.
• W4251752650 hasOpenAccess W4251752650 @default.
• W4251752650 hasPrimaryLocation W42517526501 @default.
• W4251752650 hasRelatedWork W149722017 @default.
• W4251752650 hasRelatedWork W1546768578 @default.
• W4251752650 hasRelatedWork W1792182519 @default.
• W4251752650 hasRelatedWork W1951806018 @default.
• W4251752650 hasRelatedWork W1986999852 @default.
• W4251752650 hasRelatedWork W2024916400 @default.
• W4251752650 hasRelatedWork W2156749160 @default.
• W4251752650 hasRelatedWork W2158144878 @default.
• W4251752650 hasRelatedWork W4249094903 @default.
• W4251752650 hasRelatedWork W2274122319 @default.

• next