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- W4251931705 abstract "Abstract Obesity and type 2 diabetes mellitus (T2DM) have reached epidemic proportions worldwide. While characterized by chronic hyperglycemia, the underlying cause of T2DM is insulin resistance—most often related to an increase in abdominal adiposity caused by obesity. The goal of treatment of T2DM is to put the disease into remission by targeting the underlying insulin resistance. The observation that dietary carbohydrate is the major factor to cause glycosuria and hyperglycemia, has been known since the early days of modern medicine. As a result, low-carbohydrate, ketogenic diets were employed to treat obesity and diabetes in the nineteenth and early twentieth centuries. This chapter reviews the rationale and recent clinical research supporting the use of a low-carbohydrate, ketogenic diet in individuals with obesity and diabetes. For individuals affected by obesity-related T2DM, clinical studies have shown that carbohydrate restriction and weight loss can improve hyperglycemia, obesity, and T2DM." @default.
- W4251931705 created "2022-05-12" @default.
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- W4251931705 date "2016-10-01" @default.
- W4251931705 modified "2023-09-23" @default.
- W4251931705 title "Ketogenic Diets as Highly Effective Treatments for Diabetes Mellitus and Obesity" @default.
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- W4251931705 doi "https://doi.org/10.1093/med/9780190497996.003.0037" @default.
- W4251931705 hasPublicationYear "2016" @default.
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