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- W4251994310 abstract "Fungal infections are the most common opportunistic infections occurring in HIV-infected patients, though their incidence has decreased dramatically with the introduction of combination antiretroviral therapy (cART). Most cases occur in untreated/non-compliant patients or patients whose multiple antiretroviral regimens have failed. They are a good marker of the severity of cellular immunodepression. <italic>Pneumocystis jirovecii</italic> pneumonia remains a frequent opportunistic infection in rich resource settings, and cryptococcosis a major problem in the Southern Hemisphere. In endemic areas, infections due to dimorphic fungi are an important group. An exhaustive search for dissemination should be made in HIV-infected patients—at least for those at an advanced stage of immune deficiency. Introduction of cART in combination with antifungal treatment depends on the risk of acquired immune deficiency syndrome (AIDS) progression, and on the risk of cumulative toxicity and the immune reconstitution inflammatory syndrome if introduced too early. Fungal infections remain a problem in the cART era." @default.
- W4251994310 created "2022-05-12" @default.
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- W4251994310 date "2017-12-01" @default.
- W4251994310 modified "2023-10-14" @default.
- W4251994310 title "Fungal infections among patients with AIDS" @default.
- W4251994310 doi "https://doi.org/10.1093/med/9780198755388.003.0033" @default.
- W4251994310 hasPublicationYear "2017" @default.
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