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- W4252014457 abstract "Haemorrheological factors have been shown to be affected in many kings of vascular disease. The present study was undertaken to correlate these factors in normal subjects and patients suffering from peripheral arterial disease. Twenty-two patients were investigated; they had moderate or severe intermittent claudication, extent of disease being confirmed by aorto-arteriography and ankle-systolic pressure studies. Twenty-five controls with no symptoms or signs of arterial disease were selected withcomparable age and sex distribution. Whole blood viscosity was measured at shear rates of 230 secs-1 and 23 sees-1 at 37°C using a Weils Brookfield cone plate microvisco meter. Plasma viscosity was also measured in an identical manner. Erythrocyte flexibility was measured by centrifuge technique and fibrinogen concentration as well as haematocrit by standard techniques. The fibrinogen concentration appeared to be the only significant parameter; the mean concentration in patients with peripheral vascular disease of 463 ± 73mg/100ml in the control group ( 〈 0.05). Although whole blood viscosity was high in patients, when corrected t. a common haematocrit, there was no significant difference between patients and controls The same megative correlation was found for plasma viscosity. The red cell flexibility was found to be increased in patients as compared to the control group, but this effect appeared to be simply proportional to the fibrinogen concentration." @default.
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- W4252014457 date "1979-01-01" @default.
- W4252014457 modified "2023-10-18" @default.
- W4252014457 title "Viscosity and Red Cell Deformity in Arterial Disease" @default.
- W4252014457 doi "https://doi.org/10.1055/s-0039-1684517" @default.
- W4252014457 hasPublicationYear "1979" @default.
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