Matches in SemOpenAlex for { <https://semopenalex.org/work/W4252093448> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4252093448 abstract "Abstract Surveillance strategies to detect colonization is an important tool to prevent and control the spread of microorganisms especially among Hematopoietic Stem Cell Transplant (HSCT) patients. Colonization by Multidrug-resistant organisms (MDRO) has been evaluated as a risk factor for blood stream infection (BSI) in HSCT patients. The aim of this study was to evaluate the use of routine surveillance culture to screening colonization and infection by carbapenem-resistant Enterobacteriaceae (CRE), carbapenem-resistant Pseudomonas aeruginosa (CRPa) and vancomycin-resistant enterococci (VRE) in a HSCT unit. Methods Surveillance cultures were collected from patients admitted to the HSCT unit over one-year, with swabs for cultures on admission and then weekly until discharge. We compared surveillance culture positivity for each site and agent, also clinical and epidemiological data according to the colonization status. Results 200 HSCT patients underwent surveillance, with 1.323 samples collected. Infection due to MDRO occurred in 52 (21.5%) patients, among them 45 (86.5%) were blood stream infection (BSI) and 12 (23%) had positive surveillance culture before infection. 554 (41.8%) surveillance cultures were performed for CRPa, 413 (31.2%) for VRE, and 356 (27%) for CRE. Of these, 179 (13.5%) surveillance culture were positive, with greater positivity for oropharynx (6, 35.3%) CRPa, and rectal samples (16, 20.7%) for CRE. Being colonized by any MDRO, CRE (p <0.001) and CRPa (p = 0.027) was associated with a higher risk of infection in the bivariate analysis but being colonized was not associated with risk of death. Conclusion Previous colonization by MDRO was a significant risk factor for infection by these pathogens, mainly colonization by CRE. Overall, rectal swab was the best site with the higher positivity, and the oropharynx was also an option for CRPa investigation. Feces culture showed low positivity and should be avoided. Although the impact of the strategy on the mortality of patients undergoing HSCT is not clear, VRE surveillance should be questioned in auto-HSCT patients as it has an additional cost and little impact on survival." @default.
- W4252093448 created "2022-05-12" @default.
- W4252093448 creator A5003824515 @default.
- W4252093448 creator A5007202804 @default.
- W4252093448 creator A5022892800 @default.
- W4252093448 creator A5045164159 @default.
- W4252093448 creator A5049922792 @default.
- W4252093448 creator A5060121830 @default.
- W4252093448 creator A5077539859 @default.
- W4252093448 creator A5083310176 @default.
- W4252093448 creator A5085557105 @default.
- W4252093448 creator A5086111895 @default.
- W4252093448 date "2020-11-18" @default.
- W4252093448 modified "2023-09-27" @default.
- W4252093448 title "Usefulness of surveillance Cultures for Carbapenem-resistant Enterobacteriaceae, Carbapenem-resistant Pseudomonas aeruginosa and Vancomycin-resistant Enterococci in Hematopoietic Stem Cell Transplant Unit" @default.
- W4252093448 doi "https://doi.org/10.21203/rs.3.rs-109628/v1" @default.
- W4252093448 hasPublicationYear "2020" @default.
- W4252093448 type Work @default.
- W4252093448 citedByCount "0" @default.
- W4252093448 crossrefType "posted-content" @default.
- W4252093448 hasAuthorship W4252093448A5003824515 @default.
- W4252093448 hasAuthorship W4252093448A5007202804 @default.
- W4252093448 hasAuthorship W4252093448A5022892800 @default.
- W4252093448 hasAuthorship W4252093448A5045164159 @default.
- W4252093448 hasAuthorship W4252093448A5049922792 @default.
- W4252093448 hasAuthorship W4252093448A5060121830 @default.
- W4252093448 hasAuthorship W4252093448A5077539859 @default.
- W4252093448 hasAuthorship W4252093448A5083310176 @default.
- W4252093448 hasAuthorship W4252093448A5085557105 @default.
- W4252093448 hasAuthorship W4252093448A5086111895 @default.
- W4252093448 hasBestOaLocation W42520934481 @default.
- W4252093448 hasConcept C107130276 @default.
- W4252093448 hasConcept C126322002 @default.
- W4252093448 hasConcept C166888038 @default.
- W4252093448 hasConcept C177713679 @default.
- W4252093448 hasConcept C2776927270 @default.
- W4252093448 hasConcept C2777408962 @default.
- W4252093448 hasConcept C2777637488 @default.
- W4252093448 hasConcept C2778980435 @default.
- W4252093448 hasConcept C2779489039 @default.
- W4252093448 hasConcept C2780585763 @default.
- W4252093448 hasConcept C2910137292 @default.
- W4252093448 hasConcept C2911091166 @default.
- W4252093448 hasConcept C501593827 @default.
- W4252093448 hasConcept C523546767 @default.
- W4252093448 hasConcept C54355233 @default.
- W4252093448 hasConcept C62558387 @default.
- W4252093448 hasConcept C71924100 @default.
- W4252093448 hasConcept C86803240 @default.
- W4252093448 hasConcept C89423630 @default.
- W4252093448 hasConceptScore W4252093448C107130276 @default.
- W4252093448 hasConceptScore W4252093448C126322002 @default.
- W4252093448 hasConceptScore W4252093448C166888038 @default.
- W4252093448 hasConceptScore W4252093448C177713679 @default.
- W4252093448 hasConceptScore W4252093448C2776927270 @default.
- W4252093448 hasConceptScore W4252093448C2777408962 @default.
- W4252093448 hasConceptScore W4252093448C2777637488 @default.
- W4252093448 hasConceptScore W4252093448C2778980435 @default.
- W4252093448 hasConceptScore W4252093448C2779489039 @default.
- W4252093448 hasConceptScore W4252093448C2780585763 @default.
- W4252093448 hasConceptScore W4252093448C2910137292 @default.
- W4252093448 hasConceptScore W4252093448C2911091166 @default.
- W4252093448 hasConceptScore W4252093448C501593827 @default.
- W4252093448 hasConceptScore W4252093448C523546767 @default.
- W4252093448 hasConceptScore W4252093448C54355233 @default.
- W4252093448 hasConceptScore W4252093448C62558387 @default.
- W4252093448 hasConceptScore W4252093448C71924100 @default.
- W4252093448 hasConceptScore W4252093448C86803240 @default.
- W4252093448 hasConceptScore W4252093448C89423630 @default.
- W4252093448 hasLocation W42520934481 @default.
- W4252093448 hasOpenAccess W4252093448 @default.
- W4252093448 hasPrimaryLocation W42520934481 @default.
- W4252093448 hasRelatedWork W12160531 @default.
- W4252093448 hasRelatedWork W15587432 @default.
- W4252093448 hasRelatedWork W18739995 @default.
- W4252093448 hasRelatedWork W2407127 @default.
- W4252093448 hasRelatedWork W5228542 @default.
- W4252093448 hasRelatedWork W6983162 @default.
- W4252093448 hasRelatedWork W7706604 @default.
- W4252093448 hasRelatedWork W771018 @default.
- W4252093448 hasRelatedWork W8067146 @default.
- W4252093448 hasRelatedWork W8925167 @default.
- W4252093448 isParatext "false" @default.
- W4252093448 isRetracted "false" @default.
- W4252093448 workType "article" @default.