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- W4252097192 abstract "GC/MS is widely used for the analysis of urinary organic acids for the chemical diagnosis of organic acidurias such as methylmalonic acidemia, propionic acidemia, isovaleric acidemia, glutaric aciduria type I, and multiple carboxylase deficiency. In this study, a rapid and simple preparation method for this analysis was developed in order to improve the laboratory productivity and the working environment. The solvent extraction and trimethylsilyl derivatization steps of the conventional method were improved by reducing the volume of urine sample and extraction solvent and by applying the flash-heater derivatization, respectively. The new method was successfully applied to the chemical diagnoses of five organic acidurias." @default.
- W4252097192 created "2022-05-12" @default.
- W4252097192 date "1990-12-01" @default.
- W4252097192 modified "2023-09-25" @default.
- W4252097192 title "Subject index" @default.
- W4252097192 doi "https://doi.org/10.1016/0009-8981(90)90139-j" @default.
- W4252097192 hasPublicationYear "1990" @default.
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