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- W4252582554 abstract "This chapter presents a fractal analysis to analyze the binding and dissociation kinetics on a biosensor surface of putrescene in solution to a PDDA/APTES/MWCNT/PuO-modified GCE, and various concentrations of VEGF in solution to sFlt-1 immobilized on a sensor chip surface. VEGF plays an important role in angiogenesis, and if the formation of the new capillaries can be blocked then presumably the growth of the tumor can be stopped. The fractal analysis is used to provide a better understanding of the kinetics of reactions involving cancer biomarkers or cancer-related analytes, and to relate the binding and the dissociation rate coefficients with the degree of heterogeneity or fractal dimension present on the sensor chip surface. The expressions obtained for the binding and the dissociation rate coefficients for a single- and dual-fractal analysis as a function of the fractal dimension indicate a high sensitivity of these rate coefficients on their respective fractal dimensions on the SPR sensor chip surface." @default.
- W4252582554 created "2022-05-12" @default.
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- W4252582554 date "2006-01-01" @default.
- W4252582554 modified "2023-09-26" @default.
- W4252582554 title "Fractal Analysis of Binding and Dissociation Kinetics and Interactions of Cancer Markers on Biosensor Surfaces" @default.
- W4252582554 doi "https://doi.org/10.1016/b978-044452784-4/50006-x" @default.
- W4252582554 hasPublicationYear "2006" @default.
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