Matches in SemOpenAlex for { <https://semopenalex.org/work/W4252623086> ?p ?o ?g. }
- W4252623086 endingPage "422" @default.
- W4252623086 startingPage "413" @default.
- W4252623086 abstract "Objective. To compare the efficacy and safety of atosiban and terbutaline for the inhibition of preterm labor. Methods. Two hundred and forty-nine women diagnosed with preterm labor at 23–33 weeks of gestation were enrolled of whom 245 women received treatment, 116 with atosiban and 129 with terbutaline. At randomization, women were stratified by gestational age (≤28 weeks and >28 weeks). Atosiban (iv bolus dose of 6.75 mg, then 300 μg/min for 3 h and 100 μg/min thereafter) and terbutaline (5–20 μg/min) were administered by iv infusion for 13–18 h. Re-treatment with study drug or an alternative tocolytic agent was allowed. Tocolytic effectiveness was assessed in terms of the number of women undelivered after 48 hours and 7 days and efficacy and tolerability in terms of the number of women remaining undelivered and not requiring alternative tocolytic therapy after 48 hours and 7 days of starting therapy. Safety was assessed in terms of maternal side effects and neonatal morbidity. Results. Tocolytic effectiveness at 48 hours was 86.1% vs 85.3%; p=0.783, and after 7 days it was 76.5% vs 67.4%; p=0.067, in the atosiban and terbutaline groups, respectively. Tocolytic efficacy and tolerability after 48 hours was 72.2% vs 68.2%; p=0.51 and after 7 days was 55.6% vs 43.4%; p=0.08 in the atosiban and terbutaline groups, respectively. Overall, there were fewer clinically important adverse events with atosiban than with terbutaline. Conclusions. The efficacy of atosiban in the inhibition of preterm labor was shown to be comparable to terbutaline. Atosiban had a superior safety profile compared with terbutaline in terms of maternal and fetal adverse events, and comparable infant outcomes." @default.
- W4252623086 created "2022-05-12" @default.
- W4252623086 date "2001-05-01" @default.
- W4252623086 modified "2023-10-18" @default.
- W4252623086 title "The oxytocin antagonist atosiban <i>versus</i> the β-agonist terbutaline in the treatment of preterm labor" @default.
- W4252623086 cites W1681612537 @default.
- W4252623086 cites W1973351218 @default.
- W4252623086 cites W1975489317 @default.
- W4252623086 cites W1978775463 @default.
- W4252623086 cites W1981492357 @default.
- W4252623086 cites W1993367716 @default.
- W4252623086 cites W1996553880 @default.
- W4252623086 cites W2000399626 @default.
- W4252623086 cites W2000763218 @default.
- W4252623086 cites W2004814270 @default.
- W4252623086 cites W2005750176 @default.
- W4252623086 cites W2018231713 @default.
- W4252623086 cites W2021911837 @default.
- W4252623086 cites W2022615189 @default.
- W4252623086 cites W2029129878 @default.
- W4252623086 cites W2036907220 @default.
- W4252623086 cites W2037143193 @default.
- W4252623086 cites W2037507674 @default.
- W4252623086 cites W2038421026 @default.
- W4252623086 cites W2052460545 @default.
- W4252623086 cites W2061462798 @default.
- W4252623086 cites W2071096462 @default.
- W4252623086 cites W2074422549 @default.
- W4252623086 cites W2081592308 @default.
- W4252623086 cites W2082726982 @default.
- W4252623086 cites W2085929052 @default.
- W4252623086 cites W2090835392 @default.
- W4252623086 cites W2093269059 @default.
- W4252623086 cites W2093826550 @default.
- W4252623086 cites W2106961856 @default.
- W4252623086 cites W2126298579 @default.
- W4252623086 cites W2130559132 @default.
- W4252623086 cites W2143167631 @default.
- W4252623086 cites W2143261506 @default.
- W4252623086 cites W2169830226 @default.
- W4252623086 cites W2314376387 @default.
- W4252623086 cites W2440011706 @default.
- W4252623086 cites W4241199295 @default.
- W4252623086 cites W4248096658 @default.
- W4252623086 cites W4301341292 @default.
- W4252623086 doi "https://doi.org/10.1034/j.1600-0412.2001.d01-456.x" @default.
- W4252623086 hasPublicationYear "2001" @default.
- W4252623086 type Work @default.
- W4252623086 citedByCount "35" @default.
- W4252623086 countsByYear W42526230862012 @default.
- W4252623086 countsByYear W42526230862014 @default.
- W4252623086 countsByYear W42526230862016 @default.
- W4252623086 crossrefType "journal-article" @default.
- W4252623086 hasConcept C126322002 @default.
- W4252623086 hasConcept C131872663 @default.
- W4252623086 hasConcept C197934379 @default.
- W4252623086 hasConcept C2776042228 @default.
- W4252623086 hasConcept C2778375690 @default.
- W4252623086 hasConcept C2778376644 @default.
- W4252623086 hasConcept C2779234561 @default.
- W4252623086 hasConcept C2780252434 @default.
- W4252623086 hasConcept C2780931799 @default.
- W4252623086 hasConcept C2908881489 @default.
- W4252623086 hasConcept C3019152611 @default.
- W4252623086 hasConcept C42219234 @default.
- W4252623086 hasConcept C46973012 @default.
- W4252623086 hasConcept C54355233 @default.
- W4252623086 hasConcept C71924100 @default.
- W4252623086 hasConcept C86803240 @default.
- W4252623086 hasConceptScore W4252623086C126322002 @default.
- W4252623086 hasConceptScore W4252623086C131872663 @default.
- W4252623086 hasConceptScore W4252623086C197934379 @default.
- W4252623086 hasConceptScore W4252623086C2776042228 @default.
- W4252623086 hasConceptScore W4252623086C2778375690 @default.
- W4252623086 hasConceptScore W4252623086C2778376644 @default.
- W4252623086 hasConceptScore W4252623086C2779234561 @default.
- W4252623086 hasConceptScore W4252623086C2780252434 @default.
- W4252623086 hasConceptScore W4252623086C2780931799 @default.
- W4252623086 hasConceptScore W4252623086C2908881489 @default.
- W4252623086 hasConceptScore W4252623086C3019152611 @default.
- W4252623086 hasConceptScore W4252623086C42219234 @default.
- W4252623086 hasConceptScore W4252623086C46973012 @default.
- W4252623086 hasConceptScore W4252623086C54355233 @default.
- W4252623086 hasConceptScore W4252623086C71924100 @default.
- W4252623086 hasConceptScore W4252623086C86803240 @default.
- W4252623086 hasIssue "5" @default.
- W4252623086 hasLocation W42526230861 @default.
- W4252623086 hasOpenAccess W4252623086 @default.
- W4252623086 hasPrimaryLocation W42526230861 @default.
- W4252623086 hasRelatedWork W142678202 @default.
- W4252623086 hasRelatedWork W1996553880 @default.
- W4252623086 hasRelatedWork W2025367113 @default.
- W4252623086 hasRelatedWork W2030021090 @default.
- W4252623086 hasRelatedWork W2059158232 @default.
- W4252623086 hasRelatedWork W2088130339 @default.
- W4252623086 hasRelatedWork W2161900342 @default.
- W4252623086 hasRelatedWork W2328665911 @default.
- W4252623086 hasRelatedWork W2419299211 @default.