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- W4252648013 abstract "Multiple system atrophy (MSA) is a fatal neurodegenerative disorder presenting with autonomic failure and motor impairment, primarily comprising L-dopa-resistant parkinsonism but occasionally involving cerebellar ataxia. These features result from progressive multisystem neuronal loss that is associated with oligodendroglial alpha-synuclein inclusions. The growing number of animal models for MSA reflects the search for a preclinical test-bed for elucidating MSA pathogenesis and for developing novel therapeutic interventions. Here, the currently available MSA animal models will be reviewed and leads for future research will be identified." @default.
- W4252648013 created "2022-05-12" @default.
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- W4252648013 date "2005-09-01" @default.
- W4252648013 modified "2023-10-14" @default.
- W4252648013 title "Animal models of multiple system atrophy" @default.
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- W4252648013 doi "https://doi.org/10.1016/j.tins.2005.07.002" @default.
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