Matches in SemOpenAlex for { <https://semopenalex.org/work/W4252685310> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4252685310 endingPage "1293" @default.
- W4252685310 startingPage "1293" @default.
- W4252685310 abstract "We thank Drs. Koller and Rosenkranz for their interest in our meta-analysis. They suggest that further study of NAC for the prevention of contrast nephropathy may be unjustified, given the negligible cost and side effect profile of this agent. Further, they allude to the difficulties faced by clinicians in deciding how best to prevent contrast nephropathy in their patients. We struggled with these issues during preparation of our manuscript, and did not mean to imply that clinicians should not use NAC. Rather, as we stated in our article, we believe that data are insufficient to recommend that NAC become the standard of care for patients receiving radiocontrast. This distinction is important because although the costs associated with NAC administration may be negligible, the potential consequences of recommending an ineffective therapy as the standard of care are not—from the perspective of both clinicians and scientists. For clinicians, NAC use may provide a false sense of security—hydration may be ignored, other nephrotoxic medications may not be discontinued as they should be, or unnecessary contrast studies might be performed because of the perception that NAC reduces the risk of contrast nephropathy. For scientists, such a recommendation may stifle further research to find more effective prophylaxis. In addition, prematurely adopting NAC as the standard of care would jeopardize the feasibility of placebo controlled trials in the future. We fully agree that clinicians should consider the use of NAC (together with other interventions that reduce the risk of contrast nephropathy) in patients who must receive radiocontrast. However, like Drs. Koller and Rosenkranz, we believe that further work is required to define the optimal strategy for prevention of this serious complication—with or without the use of NAC." @default.
- W4252685310 created "2022-05-12" @default.
- W4252685310 creator A5004597942 @default.
- W4252685310 creator A5034928512 @default.
- W4252685310 creator A5042956432 @default.
- W4252685310 date "2004-09-01" @default.
- W4252685310 modified "2023-09-30" @default.
- W4252685310 title "Reply from the Authors" @default.
- W4252685310 doi "https://doi.org/10.1111/j.1523-1755.2004.884_11.x" @default.
- W4252685310 hasPublicationYear "2004" @default.
- W4252685310 type Work @default.
- W4252685310 citedByCount "0" @default.
- W4252685310 crossrefType "journal-article" @default.
- W4252685310 hasAuthorship W4252685310A5004597942 @default.
- W4252685310 hasAuthorship W4252685310A5034928512 @default.
- W4252685310 hasAuthorship W4252685310A5042956432 @default.
- W4252685310 hasBestOaLocation W42526853101 @default.
- W4252685310 hasConcept C126189478 @default.
- W4252685310 hasConcept C126322002 @default.
- W4252685310 hasConcept C134018914 @default.
- W4252685310 hasConcept C142724271 @default.
- W4252685310 hasConcept C159110408 @default.
- W4252685310 hasConcept C17744445 @default.
- W4252685310 hasConcept C177713679 @default.
- W4252685310 hasConcept C199539241 @default.
- W4252685310 hasConcept C204787440 @default.
- W4252685310 hasConcept C27081682 @default.
- W4252685310 hasConcept C27415008 @default.
- W4252685310 hasConcept C2778569047 @default.
- W4252685310 hasConcept C2779473830 @default.
- W4252685310 hasConcept C2780091579 @default.
- W4252685310 hasConcept C2781184683 @default.
- W4252685310 hasConcept C555293320 @default.
- W4252685310 hasConcept C71924100 @default.
- W4252685310 hasConceptScore W4252685310C126189478 @default.
- W4252685310 hasConceptScore W4252685310C126322002 @default.
- W4252685310 hasConceptScore W4252685310C134018914 @default.
- W4252685310 hasConceptScore W4252685310C142724271 @default.
- W4252685310 hasConceptScore W4252685310C159110408 @default.
- W4252685310 hasConceptScore W4252685310C17744445 @default.
- W4252685310 hasConceptScore W4252685310C177713679 @default.
- W4252685310 hasConceptScore W4252685310C199539241 @default.
- W4252685310 hasConceptScore W4252685310C204787440 @default.
- W4252685310 hasConceptScore W4252685310C27081682 @default.
- W4252685310 hasConceptScore W4252685310C27415008 @default.
- W4252685310 hasConceptScore W4252685310C2778569047 @default.
- W4252685310 hasConceptScore W4252685310C2779473830 @default.
- W4252685310 hasConceptScore W4252685310C2780091579 @default.
- W4252685310 hasConceptScore W4252685310C2781184683 @default.
- W4252685310 hasConceptScore W4252685310C555293320 @default.
- W4252685310 hasConceptScore W4252685310C71924100 @default.
- W4252685310 hasIssue "3" @default.
- W4252685310 hasLocation W42526853101 @default.
- W4252685310 hasOpenAccess W4252685310 @default.
- W4252685310 hasPrimaryLocation W42526853101 @default.
- W4252685310 hasRelatedWork W1494328843 @default.
- W4252685310 hasRelatedWork W2020579547 @default.
- W4252685310 hasRelatedWork W2021100442 @default.
- W4252685310 hasRelatedWork W2074497010 @default.
- W4252685310 hasRelatedWork W2083990889 @default.
- W4252685310 hasRelatedWork W2357284407 @default.
- W4252685310 hasRelatedWork W2598660702 @default.
- W4252685310 hasRelatedWork W2613098449 @default.
- W4252685310 hasRelatedWork W2971012660 @default.
- W4252685310 hasRelatedWork W4205726400 @default.
- W4252685310 hasVolume "66" @default.
- W4252685310 isParatext "false" @default.
- W4252685310 isRetracted "false" @default.
- W4252685310 workType "article" @default.