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- W4252839596 abstract "γδ T cells represent a critical bridge between the dichotomous innate and adaptive immune system. These cells exhibit an invariant T cell receptor. A similar pattern of invariant T cell receptor is observed amidst natural killer cells and other less mature lymphocytes. Primary cutaneous γδ T cell lymphoma has a characteristic clinical presentation consisting of ulcerative nodules involving the extremities and associated with an aggressive clinical course. The process exactly replicated a γδ T cell lymphoma, including intraepidermal highly atypical cells and a very abnormal phenotypic profile, which included cells that did not express CD4, CD8 or and also showed a loss in the expression of CD5. Apparently the lesions resolved, however, with antimicrobial therapy and there was no subsequent recurrence for 5 years following diagnosis. The phenotypic profile would show a mixture of CD4 and CD8 lymphocytes along with scattered germinal centers and numerous plasma cells." @default.
- W4252839596 created "2022-05-12" @default.
- W4252839596 date "2016-01-01" @default.
- W4252839596 modified "2023-09-29" @default.
- W4252839596 title "Primary Cutaneous γ δ T Cell Lymphoma" @default.
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- W4252839596 doi "https://doi.org/10.1002/9781118776193.ch18" @default.
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