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- W4253110058 abstract "Our knowledge of DNA replication, repair and recombination is based on studies of bacterial viruses. Phage λ Red homologous recombination promotes genetic diversity, stimulates DNA replication, and repairs dsDNA breaks. The Red system is also a genetic engineering tool used to redesign bacterial chromosomes and modify eukaryotic DNA cloned into BACs. This technology of in vivo genetic engineering, recombineering, uses bacteriophage homologous recombination functions to promote genetic rearrangements in living bacteria. This highly developed technology allows nearly any desired genetic alteration to be made in Escherichia coli and other bacteria. Coupling recombineering with CRISPR-Cas9 allows recovery of rare recombination events." @default.
- W4253110058 created "2022-05-12" @default.
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- W4253110058 date "2021-01-01" @default.
- W4253110058 modified "2023-10-03" @default.
- W4253110058 title "Bacteriophage: Red Recombination System and the Development of Recombineering Technologies" @default.
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- W4253110058 doi "https://doi.org/10.1016/b978-0-12-809633-8.07023-0" @default.
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