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- W4253126867 endingPage "2073" @default.
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- W4253126867 abstract "<ns4:p>The direct link between lipid metabolism alterations and the increase of cardiovascular risk are well documented. Dyslipidemias, including isolated high LDL-c or mixed dyslipidemia, such as those seen in diabetes (hypertriglyceridemia, high LDL-c or low HDL-c), correlate with a significant risk of cardiovascular and cerebrovascular disease worldwide. This review analyzes the current knowledge concerning the genetic basis of lipid metabolism alterations, emphasizing lipoprotein lipase gene mutations and the HindIII polymorphism, which are associated with decreased levels of triglycerides and LDL-c, as well as higher levels of HDL-c. These patterns would be associated with decreased global morbidity and mortality, providing protection against cardiovascular and cerebrovascular diseases.</ns4:p>" @default.
- W4253126867 created "2022-05-12" @default.
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- W4253126867 date "2017-11-30" @default.
- W4253126867 modified "2023-10-16" @default.
- W4253126867 title "Dyslipidemia: Genetics, lipoprotein lipase and HindIII polymorphism" @default.
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- W4253126867 doi "https://doi.org/10.12688/f1000research.12938.1" @default.
- W4253126867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30345000" @default.
- W4253126867 hasPublicationYear "2017" @default.
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