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- W4253155124 abstract "Halobacterium salinarum is a halophilic (salt-loving) member of the Archaea that grows in concentrations of sodium chloride (NaCl) near or at saturation. Initially isolated from salted fish a century ago, Hbt. salinarum first drew general attention with the 1971 discovery of bacteriorhodopsin, the light-driven proton pump isolated from the purple membrane of this organism. Since then, studies of Hbt. salinarum have led to numerous ground-breaking and paradigm-shifting discoveries, such as the first insight into membrane protein structure and the first demonstration that such proteins can be crystallized from bilayers, as well as the first example of a noneukaryal glycoprotein. Work on Hbt. salinarum, one of the species originally used to describe the Archaea, has also advanced understanding of molecular workings in the third domain; the first transformation and gene-deletion systems for Archaea were developed in Hbt. salinarum. Finally, Hbt. salinarum presents creative solutions to challenges associated with life in high salt concentrations." @default.
- W4253155124 created "2022-05-12" @default.
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- W4253155124 date "2019-07-01" @default.
- W4253155124 modified "2023-09-25" @default.
- W4253155124 title "Halobacterium salinarum" @default.
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- W4253155124 doi "https://doi.org/10.1016/j.tim.2019.02.005" @default.
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