FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4253160129> ?p ?o ?g. }

• W4253160129 endingPage "781" @default.
• W4253160129 startingPage "769" @default.
• W4253160129 abstract "Background: The rapid rise in the availability and use of pharmaceutical agents, and particularly polypharmacy, directly increases the risk for patients to experience adverse drug reactions (ADRs). There are few studies on the overall incidence and costs of ADRs. Objective: The aim of this study was to estimate the incidence and costs of emergency department (ED) visits related to ADRs for patients greater than 65 years of age using administrative data, and to describe risk factors for experiencing severe ADRs. Methods: We employed a retrospective cohort design based on population-based healthcare administrative clinical databases. Identification of ADR-related ED visits from the administrative database was based on International Classification of Diseases, 10th Revision-Canadian Enhancement (ICD-10-CA) codes for each ED visit. The incidence and costs of ADR-related ED visits and subsequent hospital admissions were estimated for all adults aged 66 years and above for the period April 2003–March 2008. Costs were standardized and reported in 2008 Canadian dollars. Logistic regression was used to detect risk factors for severe ADRs. Results: Approximately 0.75% of total annual ED visits among adults aged 66 years and above were found to be ADR-related, and among these patients 21.6% were hospitalized. In 2007, the cost of ADR-related visits was $333 per ED visit and $7528 per hospitalization for a total annual cost of $13.6 million in Ontario, or an estimated $35.7 million in Canada. Severe ADRs were associated with sex, age, comorbid disease burden, multiple drugs, multiple pharmacies, newly prescribed drugs, recent ED visit, recent hospitalization and long-term care (LTC) residence. Conclusions: ADRs are an important public health issue that threaten the safety of drug therapy and results in significant economic burden to the healthcare system. ED visits related to ADRs may be underestimated in retrospective studies using administrative data compared with prospective studies. Further research is needed to better understand the risk of experiencing severe ADRs among LTC residents." @default.
• W4253160129 created "2022-05-12" @default.
• W4253160129 creator A5032506395 @default.
• W4253160129 creator A5043946908 @default.
• W4253160129 creator A5064563250 @default.
• W4253160129 date "2012-09-01" @default.
• W4253160129 modified "2023-10-12" @default.
• W4253160129 title "Incidence and Economic Burden of Adverse Drug Reactions among Elderly Patients in Ontario Emergency Departments" @default.
• W4253160129 cites W1969879564 @default.
• W4253160129 cites W1973245422 @default.
• W4253160129 cites W1976600075 @default.
• W4253160129 cites W1982026920 @default.
• W4253160129 cites W1983149471 @default.
• W4253160129 cites W1990676371 @default.
• W4253160129 cites W1992746042 @default.
• W4253160129 cites W2000445173 @default.
• W4253160129 cites W2005287859 @default.
• W4253160129 cites W2013949127 @default.
• W4253160129 cites W2029549566 @default.
• W4253160129 cites W2031012648 @default.
• W4253160129 cites W2055195219 @default.
• W4253160129 cites W2071479785 @default.
• W4253160129 cites W2093699352 @default.
• W4253160129 cites W2103481781 @default.
• W4253160129 cites W2103559160 @default.
• W4253160129 cites W2107505481 @default.
• W4253160129 cites W2125445772 @default.
• W4253160129 cites W2126010213 @default.
• W4253160129 cites W2129168200 @default.
• W4253160129 cites W2137779847 @default.
• W4253160129 cites W2153821141 @default.
• W4253160129 cites W2154360526 @default.
• W4253160129 cites W2159278278 @default.
• W4253160129 cites W2162834782 @default.
• W4253160129 cites W2167069322 @default.
• W4253160129 cites W2329801804 @default.
• W4253160129 doi "https://doi.org/10.2165/11599540-000000000-00000" @default.
• W4253160129 hasPublicationYear "2012" @default.
• W4253160129 type Work @default.
• W4253160129 citedByCount "9" @default.
• W4253160129 countsByYear W42531601292014 @default.
• W4253160129 countsByYear W42531601292017 @default.
• W4253160129 countsByYear W42531601292019 @default.
• W4253160129 countsByYear W42531601292020 @default.
• W4253160129 countsByYear W42531601292021 @default.
• W4253160129 countsByYear W42531601292023 @default.
• W4253160129 crossrefType "journal-article" @default.
• W4253160129 hasAuthorship W4253160129A5032506395 @default.
• W4253160129 hasAuthorship W4253160129A5043946908 @default.
• W4253160129 hasAuthorship W4253160129A5064563250 @default.
• W4253160129 hasBestOaLocation W42531601291 @default.
• W4253160129 hasConcept C104863432 @default.
• W4253160129 hasConcept C118552586 @default.
• W4253160129 hasConcept C120665830 @default.
• W4253160129 hasConcept C121332964 @default.
• W4253160129 hasConcept C126322002 @default.
• W4253160129 hasConcept C151956035 @default.
• W4253160129 hasConcept C160735492 @default.
• W4253160129 hasConcept C162324750 @default.
• W4253160129 hasConcept C167135981 @default.
• W4253160129 hasConcept C187212893 @default.
• W4253160129 hasConcept C194828623 @default.
• W4253160129 hasConcept C2780724011 @default.
• W4253160129 hasConcept C2908647359 @default.
• W4253160129 hasConcept C36434225 @default.
• W4253160129 hasConcept C45827449 @default.
• W4253160129 hasConcept C50522688 @default.
• W4253160129 hasConcept C512399662 @default.
• W4253160129 hasConcept C61511704 @default.
• W4253160129 hasConcept C71924100 @default.
• W4253160129 hasConcept C99454951 @default.
• W4253160129 hasConceptScore W4253160129C104863432 @default.
• W4253160129 hasConceptScore W4253160129C118552586 @default.
• W4253160129 hasConceptScore W4253160129C120665830 @default.
• W4253160129 hasConceptScore W4253160129C121332964 @default.
• W4253160129 hasConceptScore W4253160129C126322002 @default.
• W4253160129 hasConceptScore W4253160129C151956035 @default.
• W4253160129 hasConceptScore W4253160129C160735492 @default.
• W4253160129 hasConceptScore W4253160129C162324750 @default.
• W4253160129 hasConceptScore W4253160129C167135981 @default.
• W4253160129 hasConceptScore W4253160129C187212893 @default.
• W4253160129 hasConceptScore W4253160129C194828623 @default.
• W4253160129 hasConceptScore W4253160129C2780724011 @default.
• W4253160129 hasConceptScore W4253160129C2908647359 @default.
• W4253160129 hasConceptScore W4253160129C36434225 @default.
• W4253160129 hasConceptScore W4253160129C45827449 @default.
• W4253160129 hasConceptScore W4253160129C50522688 @default.
• W4253160129 hasConceptScore W4253160129C512399662 @default.
• W4253160129 hasConceptScore W4253160129C61511704 @default.
• W4253160129 hasConceptScore W4253160129C71924100 @default.
• W4253160129 hasConceptScore W4253160129C99454951 @default.
• W4253160129 hasIssue "9" @default.
• W4253160129 hasLocation W42531601291 @default.
• W4253160129 hasOpenAccess W4253160129 @default.
• W4253160129 hasPrimaryLocation W42531601291 @default.
• W4253160129 hasRelatedWork W2026095104 @default.
• W4253160129 hasRelatedWork W2061619006 @default.
• W4253160129 hasRelatedWork W2071950799 @default.

• next