Matches in SemOpenAlex for { <https://semopenalex.org/work/W4253240499> ?p ?o ?g. }
- W4253240499 endingPage "1135" @default.
- W4253240499 startingPage "1131" @default.
- W4253240499 abstract "Abstract We present herein a short tripeptide sequence (Lys–Phe–Gly or KFG) that is situated in the juxtamembrane region of the tyrosine kinase nerve growth factor (Trk NGF) receptors. KFG self‐assembles in water and shows a reversible and concentration‐dependent switching of nanostructures from nanospheres (vesicles) to nanotubes, as evidenced by dynamic light scattering, transmission electron microscopy, and atomic force microscopy. The morphology change was associated with a transition in the secondary structure. The tripeptide vesicles have inner aqueous compartments and are stable at pH 7.4 but rupture rapidly at pH≈6. The pH‐sensitive response of the vesicles was exploited for the delivery of a chemotherapeutic anticancer drug, doxorubicin, which resulted in enhanced cytotoxicity for both drug‐sensitive and drug‐resistant cells. Efficient intracellular release of the drug was confirmed by fluorescence‐activated cell sorting analysis, fluorescence microscopy, and confocal microscopy." @default.
- W4253240499 created "2022-05-12" @default.
- W4253240499 creator A5019021675 @default.
- W4253240499 creator A5020978468 @default.
- W4253240499 creator A5049102950 @default.
- W4253240499 creator A5061086386 @default.
- W4253240499 date "2013-12-11" @default.
- W4253240499 modified "2023-10-18" @default.
- W4253240499 title "Efficacious Anticancer Drug Delivery Mediated by a pH-Sensitive Self-Assembly of a Conserved Tripeptide Derived from Tyrosine Kinase NGF Receptor" @default.
- W4253240499 cites W1596495551 @default.
- W4253240499 cites W1964553162 @default.
- W4253240499 cites W1968706269 @default.
- W4253240499 cites W1969268706 @default.
- W4253240499 cites W1972154409 @default.
- W4253240499 cites W1978421288 @default.
- W4253240499 cites W1979849149 @default.
- W4253240499 cites W1980288936 @default.
- W4253240499 cites W1988988697 @default.
- W4253240499 cites W1991126847 @default.
- W4253240499 cites W1995200008 @default.
- W4253240499 cites W1995924359 @default.
- W4253240499 cites W1997787046 @default.
- W4253240499 cites W2000364895 @default.
- W4253240499 cites W2000667952 @default.
- W4253240499 cites W2001018974 @default.
- W4253240499 cites W2001558390 @default.
- W4253240499 cites W2012304333 @default.
- W4253240499 cites W2018664598 @default.
- W4253240499 cites W2019081161 @default.
- W4253240499 cites W2027117593 @default.
- W4253240499 cites W2032760352 @default.
- W4253240499 cites W2035846395 @default.
- W4253240499 cites W2035862523 @default.
- W4253240499 cites W2036444063 @default.
- W4253240499 cites W2038989792 @default.
- W4253240499 cites W2046788321 @default.
- W4253240499 cites W2051653227 @default.
- W4253240499 cites W2062514032 @default.
- W4253240499 cites W2070986221 @default.
- W4253240499 cites W2073846786 @default.
- W4253240499 cites W2074483655 @default.
- W4253240499 cites W2080457223 @default.
- W4253240499 cites W2081534612 @default.
- W4253240499 cites W2095571709 @default.
- W4253240499 cites W2100703880 @default.
- W4253240499 cites W2115164481 @default.
- W4253240499 cites W2115219344 @default.
- W4253240499 cites W2118804904 @default.
- W4253240499 cites W2127410754 @default.
- W4253240499 cites W2131447388 @default.
- W4253240499 cites W2136986287 @default.
- W4253240499 cites W2150850636 @default.
- W4253240499 cites W2151871529 @default.
- W4253240499 cites W2154999938 @default.
- W4253240499 cites W2156674115 @default.
- W4253240499 cites W2158069016 @default.
- W4253240499 cites W2161267543 @default.
- W4253240499 cites W2167722760 @default.
- W4253240499 cites W2169411075 @default.
- W4253240499 cites W2312493851 @default.
- W4253240499 cites W2321828396 @default.
- W4253240499 cites W2329244214 @default.
- W4253240499 cites W2330938603 @default.
- W4253240499 cites W4206603795 @default.
- W4253240499 cites W4214754931 @default.
- W4253240499 cites W4229540277 @default.
- W4253240499 cites W4230001529 @default.
- W4253240499 cites W4237111679 @default.
- W4253240499 cites W4238265573 @default.
- W4253240499 cites W4238841878 @default.
- W4253240499 cites W4238940856 @default.
- W4253240499 cites W4376453918 @default.
- W4253240499 doi "https://doi.org/10.1002/ange.201307247" @default.
- W4253240499 hasPublicationYear "2013" @default.
- W4253240499 type Work @default.
- W4253240499 citedByCount "21" @default.
- W4253240499 countsByYear W42532404992014 @default.
- W4253240499 countsByYear W42532404992015 @default.
- W4253240499 countsByYear W42532404992017 @default.
- W4253240499 countsByYear W42532404992018 @default.
- W4253240499 countsByYear W42532404992019 @default.
- W4253240499 countsByYear W42532404992020 @default.
- W4253240499 countsByYear W42532404992021 @default.
- W4253240499 countsByYear W42532404992022 @default.
- W4253240499 countsByYear W42532404992023 @default.
- W4253240499 crossrefType "journal-article" @default.
- W4253240499 hasAuthorship W4253240499A5019021675 @default.
- W4253240499 hasAuthorship W4253240499A5020978468 @default.
- W4253240499 hasAuthorship W4253240499A5049102950 @default.
- W4253240499 hasAuthorship W4253240499A5061086386 @default.
- W4253240499 hasConcept C121608353 @default.
- W4253240499 hasConcept C12554922 @default.
- W4253240499 hasConcept C130316041 @default.
- W4253240499 hasConcept C134139212 @default.
- W4253240499 hasConcept C14631669 @default.
- W4253240499 hasConcept C155672457 @default.
- W4253240499 hasConcept C167392928 @default.
- W4253240499 hasConcept C170493617 @default.