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- W4253299116 abstract "Transcripts for interleukin (IL) 15 were detected in the gastric mucosal samples of 5/5 (100%) patients with no evidence of Helicobacter pylori infection and in 4/14 (28%) H. pylori-infected patients (P<0.05). Both IL-15 mRNA and IL-15 protein were detected in 1/6 (17%) patients who successfully underwent H. pylori eradication therapy, before treatment and in 5/6 (83%) cases after eradication. Even though a parallel significant (P<0.03) improvement of gastritis score occurred after eradication, the severity of gastritis did not differ according to the mucosal IL-15 expression among H. pylori-infected patients, irrespective of the CagA serology. This study demonstrates, for the first time, that transcripts for IL-15 are expressed in the human gastric mucosa. Changes occurring during H. pylori colonisation and after eradication raise the hypothesis that H. pylori may down-regulate IL-15 expression in the gastric mucosa." @default.
- W4253299116 created "2022-05-12" @default.
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- W4253299116 date "1999-06-01" @default.
- W4253299116 modified "2023-09-23" @default.
- W4253299116 title "Changes in the mucosal expression of interleukin 15 in Helicobacter pylori-associated gastritis" @default.
- W4253299116 doi "https://doi.org/10.1016/s0928-8244(99)00032-2" @default.
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