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- W4253299844 abstract "To investigate the effectiveness and safety of the homeopathic product SilAtro-5-90 in recurrent tonsillitis.In this international, pragmatic, controlled clinical trial, 256 patients (6–60 years) with moderate recurrent tonsillitis were randomized to receive either SilAtro-5-90 in addition to standard symptomatic treatment, or to receive standard treatment only. The primary outcome was the mean time period between consecutive acute throat infections (ATI) within 1 year (analyzed via repeated events analysis).During the evaluation year, the risk of getting an ATI was significantly lower (hazard ratio: 0.45, proportional means model, p = 0.0002, ITT) with SilAtro-5-90 compared to control. Tonsillitis-specific symptoms were significantly reduced (p < 0.0001, ITT) and the need of antibiotics to treat acute throat infections (p = 0.0008; ITT) decreased. 3 non-serious adverse drug reactions were reported for SilAtro-5-90.An integrative treatment approach where SilAtro-5-90 is given alongside mainstream symptomatic treatment may bring therapeutic benefit to patients suffering from recurrent tonsillitis.Trial registration: ISRCTN registry: Registration number ISRCTN19016626, registered 23 January 2013." @default.
- W4253299844 created "2022-05-12" @default.
- W4253299844 date "1999-09-01" @default.
- W4253299844 modified "2023-09-25" @default.
- W4253299844 title "Homeopathic versus conventional treatment of vertigo: a randomized double-blind controlled clinical study" @default.
- W4253299844 doi "https://doi.org/10.1016/s0965-2299(99)80140-x" @default.
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