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- W4253308403 abstract "The biosynthesis of chondroitin sulphate exemplifies the formation of connective tissue polysaccharides. Six different glycosyltransferases participate: a chain-initiating xylosyltransferase, two galactosyltransferases, two glucuro-nosyltransferases, and an N-acetylgalactosaminyltransferase. Some of their properties are discussed, particularly their substrate specificities determined with small oligosaccharide acceptors of well-defined structure. Purification of these enzymes is in its early stages and has been hampered by the membrane-bound nature of most of them. Xylosyltransferase, which is the most soluble, has been purified over 1000-fold by chromatography on an affinity matrix of Sepharose-bound Smith-degraded cartilage proteoglycan." @default.
- W4253308403 created "2022-05-12" @default.
- W4253308403 creator A5071079397 @default.
- W4253308403 date "1973-01-01" @default.
- W4253308403 modified "2023-09-28" @default.
- W4253308403 title "BIOSYNTHESIS OF CONNECTIVE TISSUE POLYSACCHARIDES" @default.
- W4253308403 doi "https://doi.org/10.1016/b978-0-408-70525-7.50008-2" @default.
- W4253308403 hasPublicationYear "1973" @default.
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